IMMUNOGENIC CAPACITY OF RIBOSOMES OF SALMONELLA-TYPHI INTERFERED WITH BY A FLAGELLIN-LIKE MATERIAL CONTAMINANT

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dc.contributor.authorCOFRE, G
dc.contributor.authorCALDERON, I
dc.contributor.authorMORA, GC
dc.date.accessioned2025-01-23T19:44:51Z
dc.date.available2025-01-23T19:44:51Z
dc.date.issued1978
dc.description.abstractThe double-immunodiffusion technique and sodium dodecyl sulfate-polyacrylamide electrophoresis were used to demonstrate the presence of flagellin-like material strongly attached to ribosomes of S. typhi Ty 2. This flagellin-like material contaminating the ribosome preparation interfers with the induction of [rabbit] antiribosome serum, promoting the formation of antisera reacting either only with flagellin or in some cases with flagellin and ribosomes, but giving a very weak reaction with the latter. The interference is also observed when purified ribosomes from a nonflagellated mutant of S. typhi (S. typhi O-901) mixed with purified S. typhi Ty 2 flagellin are utilized as antigens. The antirosome sera obtained with ribosomes from S. typhi O-901 have a considerably higher titer than those that are interfered with. These sera were able to react with ribosomes obtained from several related species and did not react with flagella-derived flagellin of S. typhi Ty 2.
dc.fuente.origenWOS
dc.identifier.eissn1098-5522
dc.identifier.issn0019-9567
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/100143
dc.identifier.wosidWOS:A1978EW13500028
dc.issue.numero1
dc.language.isoen
dc.pagina.final166
dc.pagina.inicio161
dc.revistaInfection and immunity
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleIMMUNOGENIC CAPACITY OF RIBOSOMES OF SALMONELLA-TYPHI INTERFERED WITH BY A FLAGELLIN-LIKE MATERIAL CONTAMINANT
dc.typeartículo
dc.volumen20
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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