TOXIC EFFECT OF A PHOTOINDUCED TRYPTOPHAN-RIBOFLAVIN ADDUCT ON F9-TERATOCARCINOMA CELLS AND PREIMPLANTATION MOUSE EMBRYOS

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dc.contributor.authorSILVA, E
dc.contributor.authorSALIMHANNA, M
dc.contributor.authorBECKER, MI
dc.contributor.authorDEIOANNES, A
dc.date.accessioned2025-01-23T19:25:14Z
dc.date.available2025-01-23T19:25:14Z
dc.date.issued1988
dc.description.abstractSolutions containing L-tryptophan and riboflavin exposed to visible light, under N2 atmosphere, yield a tryptophan-riboflavin adduct, able to inhibit the growth of cultured F9 teratocarcinoma cells. This same effect was found in the presence of a mixture of the tryptophan photooxidation products and the adduct, when using solutions previously irradiated with visible light in an O2 atmosphere. A cytotoxic effect was also observed with embryos incubated in the presence of a tryptophan-riboflavin adduct, in the latter case necrosis and embryo development arrest occured.
dc.fuente.origenWOS
dc.identifier.eissn1664-2821
dc.identifier.issn0300-9831
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/99455
dc.identifier.wosidWOS:A1988R787600004
dc.issue.numero4
dc.language.isoen
dc.pagina.final401
dc.pagina.inicio394
dc.revistaInternational journal for vitamin and nutrition research
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleTOXIC EFFECT OF A PHOTOINDUCED TRYPTOPHAN-RIBOFLAVIN ADDUCT ON F9-TERATOCARCINOMA CELLS AND PREIMPLANTATION MOUSE EMBRYOS
dc.typeartículo
dc.volumen58
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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