IS THERE A CORRESPONDENCE BETWEEN HALF-LIVES OF MOTOR ENDPLATE ACETYLCHOLINESTERASE AND JUNCTIONAL ACETYLCHOLINE RECEPTORS

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dc.contributor.authorINESTROSA, NC
dc.contributor.authorFERNANDEZ, HL
dc.date.accessioned2025-01-23T19:44:56Z
dc.date.available2025-01-23T19:44:56Z
dc.date.issued1977
dc.description.abstractTo study the turnover rate of motor endplate acetylcholinesterase (AChE), we have treated the hypoglossal nerve [rat] with 10 mM colchicine, a drug that produced a reversible decrease of AChE from geniohyoid muscle endplates. The return of AChE to the normal steady-state level was used to calculate an AChE half-life of 4.6 days. This value was very close to that obtained for the half-life of junctional acetylcholine receptors (AChR). Both macromolecules seem to have the same turnover rate.
dc.fuente.origenWOS
dc.identifier.eissn1872-7972
dc.identifier.issn0304-3940
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/100164
dc.identifier.wosidWOS:A1977DL43100015
dc.issue.numero1-2
dc.language.isoen
dc.pagina.final93
dc.pagina.inicio91
dc.revistaNeuroscience letters
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleIS THERE A CORRESPONDENCE BETWEEN HALF-LIVES OF MOTOR ENDPLATE ACETYLCHOLINESTERASE AND JUNCTIONAL ACETYLCHOLINE RECEPTORS
dc.typeartículo
dc.volumen5
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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