Sex differences in the prefrontal cortex and muscle oxygenation during exercise until exhaustion in endurance-trained individuals.
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Date
2025
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Abstract
Biological sex influences exercise performance, largely owing to anatomical and physiological differences in brain areas involved in cognitive motor control and in respiratory and locomotor muscles related to workload. We used near-infrared spectroscopy data to examine sex differences in haemodynamic responses and oxygenation patterns in the prefrontal cortex (PFC), m. intercostales and m. vastus lateralis during incremental exercise in 74 endurance-trained individuals. Changes (Δ) in oxyhaemoglobin (O2-Hb), deoxyhaemoglobin (H-Hb) and tissue saturation index (TSI) were analysed using a two-way ANOVA with the factors 'sex' and 'intensity'. Effect sizes (ES) were also reported by partial eta squared (ηp 2). Interactions were observed for ΔO2-Hb at the PFC [p
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Keywords
Biomedicine, Exercise training, Fatigue, Near‐infrared spectroscopy
