ANTAGONISM OF DOPAMINE-INDUCED CHEMOSENSORY INHIBITION BY ERGOT ALKALOIDS

Simple item page
dc.contributor.authorZAPATA, P
dc.contributor.authorLARRAIN, C
dc.date.accessioned2025-01-23T19:44:46Z
dc.date.available2025-01-23T19:44:46Z
dc.date.issued1978
dc.description.abstractIntracarotid and i.v. injections of ergometrine, methylergometrine, ergotamine, dihydroergotamine, dihydroergotoxine and 2-Br-.alpha.-ergocryptine depressed the frequency of chemosensory impulses, recorded from the carotid nerve of anesthetized cats. After administration of ergot alkaloids, dopamine-induced inhibition of chemosensory activity was blocked; this effect was not associated with blocking of .alpha.-adrenoceptors for ergometrine, methylergometrine, ergotamine and 2-Br-.alpha.-ergocryptine, but it coincided with .alpha.-adrenergic antagonism for dihydroergotamine and dihydroergotoxine. Ergot alkaloids can act on carotid body chemoreceptors as dopamine analogs and antagonists.
dc.fuente.origenWOS
dc.identifier.eissn1872-7972
dc.identifier.issn0304-3940
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/100122
dc.identifier.wosidWOS:A1978FK54100007
dc.issue.numero2
dc.language.isoen
dc.pagina.final136
dc.pagina.inicio131
dc.revistaNeuroscience letters
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleANTAGONISM OF DOPAMINE-INDUCED CHEMOSENSORY INHIBITION BY ERGOT ALKALOIDS
dc.typeartículo
dc.volumen8
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
Files
Collections
Artículos de revistas