Development of Electroanalytical Methods Using Different Electrodes for the Determination of Progesterone (P4) in Pharmaceutical Formulations and Human, Cow and Goat Milk

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dc.contributor.authorCruz, Victoria
dc.contributor.authorTrivino, Juan Jose
dc.contributor.authorArancibia, Veronica
dc.date.accessioned2025-01-20T20:20:58Z
dc.date.available2025-01-20T20:20:58Z
dc.date.issued2023
dc.description.abstractFor the determination of progesterone (P4) electroanalytical studies were performed using mercury electrode (HMDE) and screen-printed boron-doped diamond electrode (BDD-SPE). The effects of pH, supporting electrolyte, accumulation potential and time (E-acc, t(acc)) were studied in both systems. The optimum conditions were: i) HMDE: pH 7,0; -0,1 V and t(acc): 40 s, ii) BDD-SPE: 0,5 mol L-1 H2S ; E-acc: 0,0 V and t(acc): 120 s. Under these conditions, the detection limit was 3.1 mu g L-1 for HMDE and 45.6 mu g L-1 for BDD-SPE. Both methods were validated and applied in the P4 determination on pharmaceutical formulations and milk samples.
dc.description.funderANID (Chile) under Fondecyt
dc.fuente.origenWOS
dc.identifier.doi10.1002/elan.202200272
dc.identifier.eissn1521-4109
dc.identifier.issn1040-0397
dc.identifier.urihttps://doi.org/10.1002/elan.202200272
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/92606
dc.identifier.wosidWOS:000849808600001
dc.issue.numero3
dc.language.isoen
dc.revistaElectroanalysis
dc.rightsacceso restringido
dc.subjectProgesterone (P4)
dc.subjectHMDE
dc.subjectBDD-SPE
dc.subjectMilk samples
dc.subjectPharmaceutical formulations (Progendo (R), Progest (R), Progeffik (R))
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleDevelopment of Electroanalytical Methods Using Different Electrodes for the Determination of Progesterone (P4) in Pharmaceutical Formulations and Human, Cow and Goat Milk
dc.typeartículo
dc.volumen35
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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