Full-Wave Modeling of Transcranial Ultrasound using Volume-Surface Integral Equations and CT-Derived Heterogeneous Skull Data

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dc.catalogadordfo
dc.contributor.authorAlmuna Morales, Alberto
dc.contributor.authorAballay Fernandez, Danilo Ignacio
dc.contributor.authorGélat, Pierre
dc.contributor.authorHaqshenas, Reza
dc.contributor.authorVant Wout, Elwin
dc.date.accessioned2025-09-03T17:01:29Z
dc.date.available2025-09-03T17:01:29Z
dc.date.issued2025
dc.description.abstractTranscranial ultrasound therapy uses focused acoustic energy to induce therapeutic bioeffects in the brain. Ultrasound is transmitted through the skull, which is highly attenuating and heterogeneous, causing beam distortion, reducing focal pressure, and shifting the target location. Computational models are frequently used for predicting beam aberration, assessing cranial heating, and correcting the phase of ultrasound transducers. These models often rely on computed tomography (CT) images to build patient-specific geometries and estimate skull acoustic properties. However, the coarse voxel resolution of CT limits accuracy for differential equation solvers. This paper presents an efficient numerical method based on volume-surface integral equations to model full-wave acoustic propagation through heterogeneous skull tissue. We have shown that this approach is highly accurate on relatively coarse meshes compared to the minimum wavelength, enabling direct use of CT voxel data. The method is validated against a high-resolution boundary element model using an averaged skull representation. Simulations with a CT-based skull model and a bowl transducer show significant beam distortion and attenuation, with a focal shift of several millimeters from the homogeneous case
dc.fechaingreso.objetodigital2025-09-03
dc.format.extent22 páginas
dc.fuente.origenORCID
dc.identifier.doi10.48550/arXiv.2508.11100
dc.identifier.urihttps://doi.org/10.48550/arXiv.2508.11100
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/105546
dc.information.autorucEscuela de Ingeniería; Almuna Morales Alberto; S/I; 1064721
dc.information.autorucEscuela de Ingeniería; Aballay Fernandez Danilo Ignacio; S/I; 1133082
dc.information.autorucS/I; Vant Wout Elwin; S/I; 1024024
dc.language.isoen
dc.nota.accesocontenido parcial
dc.revistaMedical Physics
dc.rightsacceso restringido
dc.subjectMedical Physics
dc.subjectImage and Video Processing
dc.subjectNumerical Analysis
dc.subjectComputational Physics
dc.subject.ddc620
dc.subject.deweyIngenieríaes_ES
dc.titleFull-Wave Modeling of Transcranial Ultrasound using Volume-Surface Integral Equations and CT-Derived Heterogeneous Skull Data
dc.typeartículo
sipa.codpersvinculados1064721
sipa.codpersvinculados1133082
sipa.codpersvinculados1024024
sipa.trazabilidadORCID;2025-08-25
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