A COMPARISON OF THE XENOPUS-LAEVIS OOCYTE ACETYLCHOLINESTERASE WITH THE MUSCLE AND BRAIN ENZYME SUGGESTS VARIATIONS AT THE POSTTRANSLATIONAL LEVEL

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dc.contributor.authorMOYA, MA
dc.contributor.authorFUENTES, ME
dc.contributor.authorINESTROSA, NC
dc.date.accessioned2025-01-23T19:22:52Z
dc.date.available2025-01-23T19:22:52Z
dc.date.issued1991
dc.description.abstract1. Xenopus laevis oocytes express endogenously two components of the cholinergic system: the muscarinic receptors and the acetylcholinesterase (AChE).
dc.description.abstract2. A biochemical characterization of this enzyme was carried out.
dc.description.abstract3. The results established that the activity found in the oocytes correspond to 'true' AChE with a molecular weight of 65,000 Da and a sedimentation coefficient of 3-4 S.
dc.description.abstract4. The enzyme aggregates in the absence of detergent suggesting that it possess an hydrophobic character; despite that, it is not sensitive to PIPLC.
dc.description.abstract5. A comparison with the Xenopus brain and muscle AChE shows different post-translational modifications and catalytic properties with the oocyte AChE.
dc.fuente.origenWOS
dc.identifier.eissn1878-1659
dc.identifier.issn1532-0456
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/99120
dc.identifier.wosidWOS:A1991FC28400007
dc.issue.numero2-3
dc.language.isoen
dc.pagina.final305
dc.pagina.inicio299
dc.revistaComparative biochemistry and physiology c-toxicology & pharmacology
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleA COMPARISON OF THE XENOPUS-LAEVIS OOCYTE ACETYLCHOLINESTERASE WITH THE MUSCLE AND BRAIN ENZYME SUGGESTS VARIATIONS AT THE POSTTRANSLATIONAL LEVEL
dc.typeartículo
dc.volumen98
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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