A short cervix in women with preterm labor and intact membranes: A risk factor for microbial invasion of the amniotic cavity

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dc.contributor.authorGomez, R
dc.contributor.authorRomero, R
dc.contributor.authorNien, JK
dc.contributor.authorChaiworapongsa, T
dc.contributor.authorMedina, L
dc.contributor.authorKim, YM
dc.contributor.authorYoon, BH
dc.contributor.authorCarstens, M
dc.contributor.authorEspinoza, J
dc.contributor.authorIams, JD
dc.contributor.authorGonzalez, R
dc.date.accessioned2024-01-10T12:37:39Z
dc.date.available2024-01-10T12:37:39Z
dc.date.issued2005
dc.description.abstractObjective: The purpose of this study was to determine whether there was a relationship between sonographic cervical length and the presence of culture-proven microbial invasion of the ammotic cavity in women with preterm labor and intact membranes.
dc.description.abstractStudy design: Ultrasonography and amniocentesis were performed in 401 patients admitted with preterm labor (22-35 weeks) and cervical dilatation of less than or equal to 3 cm. as assessed by digital examination. Cervical length was determined by transvaginal ultrasound at admission. Outcome variables were the presence of microbial invasion of the amniotic cavity (defined as a positive amniotic fluid culture) and the occurrence of preterm delivery before 35 weeks. Contingency tables x(2) test, receiver-operator characteristic (ROC) curves, and logistic regression were used for statistical analysis.
dc.description.abstractResults: The prevalence of microbial invasion of the amniotic cavity was 7% (28/401). Spontaneous preterm delivery (less than or equal to 35 weeks) occurred in 21.4% (82/384) of patients. ROC curve analysis showed a significant relationship between the frequency of microbial invasion of the ammotic cavity and the length of the uterine cervix (area under the curve: 0.77; P <.005). Patients with a cervical length < 15 mm had a higher rate of a positive ammotic fluid culture than patients with a cervical length greater than or equal to 15 mm (26.3% [15/57] vs. 3.8% [13/344], respectively; P <.05). Moreover, patients with a short cervix (defined as < 15 mm) were more likely to deliver spontaneously before 35 weeks, 32 weeks, within 7 days, and within 48 hours of admission (P <.05 for all comparisons). Forty percent of patients (161/401) had a cervical length 30 mm. These patients had a very low risk of microbial invasion of the ammotic cavity (1.9% [3/161]), spontaneous delivery less than or equal to 35 weeks (4.5% [7/154]),less than or equal to 32 weeks (2.6% [2/76]), within 7 days (1.9% [3/154]), and within 48 hours (0% [0/154]) of admission.
dc.description.abstractConclusion: Endovaginal ultrasonographic examination of the uterine cervix in women with preterm labor identifies patients at increased risk for intrauterine infection. (C) 2005 Elsevier Inc. All rights reserved.
dc.description.funderEUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT
dc.description.funderEUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH &HUMAN DEVELOPMENT
dc.fechaingreso.objetodigital2024-03-19
dc.format.extent12 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.ajog.2004.10.624
dc.identifier.eissn1097-6868
dc.identifier.issn0002-9378
dc.identifier.pubmedidMEDLINE:15746658
dc.identifier.urihttps://doi.org/10.1016/j.ajog.2004.10.624
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/76896
dc.identifier.wosidWOS:000227477600005
dc.information.autorucMedicina;Gómez R;S/I;80926
dc.issue.numero3
dc.language.isoen
dc.nota.accesoContenido parcial
dc.pagina.final689
dc.pagina.inicio678
dc.publisherMOSBY-ELSEVIER
dc.revistaAMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
dc.rightsacceso restringido
dc.subjectuterine cervix
dc.subjectultrasound
dc.subjectchorioamnionitis
dc.subjectamniocentesis
dc.subjectpreterm delivery
dc.subjectBLOOD-CELL COUNT
dc.subjectFETAL INFLAMMATORY RESPONSE
dc.subjectWHITE-MATTER LESIONS
dc.subjectIMMEDIATE POSTPARTUM TREATMENT
dc.subjectPOLYMERASE-CHAIN-REACTION
dc.subjectUMBILICAL-CORD PLASMA
dc.subjectC-REACTIVE PROTEIN
dc.subjectINTRAUTERINE INFECTION
dc.subjectUREAPLASMA-UREALYTICUM
dc.subjectINTRAAMNIOTIC INFECTION
dc.subject.ods03 Good Health and Well-being
dc.subject.ods05 Gender Equality
dc.subject.odspa03 Salud y bienestar
dc.subject.odspa05 Igualdad de género
dc.titleA short cervix in women with preterm labor and intact membranes: A risk factor for microbial invasion of the amniotic cavity
dc.typeartículo
dc.volumen192
sipa.codpersvinculados80926
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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