Implementation of a re-linkage to care strategy in patients with chronic hepatitis C who were lost to follow-up in Latin America

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dc.contributor.authorMendizabal, Manuel
dc.contributor.authorThompson, Marcos
dc.contributor.authorGonzalez-Ballerga, Esteban
dc.contributor.authorAnders, Margarita
dc.contributor.authorCastro-Narro, Graciela E.
dc.contributor.authorPessoa, Mario G.
dc.contributor.authorCheinquer, Hugo
dc.contributor.authorMezzano, Gabriel
dc.contributor.authorPalazzo, Ana
dc.contributor.authorRidruejo, Ezequiel
dc.contributor.authorDescalzi, Valeria
dc.contributor.authorVelarde-Ruiz Velasco, Jose A.
dc.contributor.authorMarciano, Sebastian
dc.contributor.authorMunoz, Linda
dc.contributor.authorSchinoni, Maria, I
dc.contributor.authorPoniachik, Jaime
dc.contributor.authorPerazzo, Rosalia
dc.contributor.authorCerda, Eira
dc.contributor.authorFuster, Francisco
dc.contributor.authorVaron, Adriana
dc.contributor.authorRuiz Garcia, Sandro
dc.contributor.authorSoza, Alejandro
dc.contributor.authorCabrera, Cecilia
dc.contributor.authorGomez-Aldana, Andres J.
dc.contributor.authorde Maria Beltran, Flor
dc.contributor.authorGerona, Solange
dc.contributor.authorCocozzella, Daniel
dc.contributor.authorBessone, Fernando
dc.contributor.authorHernandez, Nelia
dc.contributor.authorAlonso, Cristina
dc.contributor.authorFerreiro, Melina
dc.contributor.authorAntinucci, Florencia
dc.contributor.authorTorre, Aldo
dc.contributor.authorMoutinho, Bruna D.
dc.contributor.authorCoelho Borges, Silvia
dc.contributor.authorGomez, Fernando
dc.contributor.authorDolores Murga, Maria
dc.contributor.authorPinero, Federico
dc.contributor.authorSotera, Gisela F.
dc.contributor.authorOcampo, Jhonier A.
dc.contributor.authorCortes Mollinedo, Valeria A.
dc.contributor.authorSimian, Daniela
dc.contributor.authorSilva, Marcelo O.
dc.date.accessioned2025-01-20T20:07:09Z
dc.date.available2025-01-20T20:07:09Z
dc.date.issued2023
dc.description.abstractTo achieve WHO's goal of eliminating hepatitis C virus (HCV), innovative strategies must be designed to diagnose and treat more patients. Therefore, we aimed to describe an implementation strategy to identify patients with HCV who were lost to follow-up (LTFU) and offer them re-linkage to HCV care. We conducted an implementation study utilizing a strategy to contact patients with HCV who were not under regular follow-up in 13 countries from Latin America. Patients with HCV were identified by the international classification of diseases (ICD-9/10) or equivalent. Medical records were then reviewed to confirm the diagnosis of chronic HCV infection defined by anti-HCV+ and detectable HCV-RNA. Identified patients who were not under follow-up by a liver specialist were contacted by telephone or email, and offered a medical reevaluation. A total of 10,364 patients were classified to have HCV. After reviewing their medical charts, 1349 (13%) had undetectable HCV-RNA or were wrongly coded. Overall, 9015 (86.9%) individuals were identified with chronic HCV infection. A total of 5096 (56.5%) patients were under routine HCV care and 3919 (43.5%) had been LTFU. We were able to contact 1617 (41.3%) of the 3919 patients who were LTFU at the primary medical institution, of which 427 (26.4%) were cured at a different institutions or were dead. Of the remaining patients, 906 (76.1%) were candidates for retrieval. In our cohort, about one out of four patients with chronic HCV who were LTFU were candidates to receive treatment. This strategy has the potential to be effective, accessible and significantly impacts on the HCV care cascade.
dc.description.funderGilead Sciences
dc.fuente.origenWOS
dc.identifier.doi10.1111/jvh.13758
dc.identifier.eissn1365-2893
dc.identifier.issn1352-0504
dc.identifier.urihttps://doi.org/10.1111/jvh.13758
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/91769
dc.identifier.wosidWOS:000868495400001
dc.issue.numero1
dc.language.isoen
dc.pagina.final63
dc.pagina.inicio56
dc.revistaJournal of viral hepatitis
dc.rightsacceso restringido
dc.subjectcare cascade
dc.subjectelimination
dc.subjecthepatitis C virus
dc.subjectLatin America
dc.subjectretrieval
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleImplementation of a re-linkage to care strategy in patients with chronic hepatitis C who were lost to follow-up in Latin America
dc.typeartículo
dc.volumen30
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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