Survival rates of advanced estrogen-receptor positive breast cancer. Analysis of 211 cases

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dc.contributor.authorSanchez, Cesar
dc.contributor.authorDominguez, Francisco
dc.contributor.authorGalindo, Hector
dc.contributor.authorCamus, Mauricio
dc.contributor.authorOddo, David
dc.contributor.authorVillarroel, Alejandra
dc.contributor.authorRazmilic, Dravna
dc.contributor.authorPena, Jose
dc.contributor.authorElena Navarro, Maria
dc.contributor.authorMedina, Lidia
dc.contributor.authorMerino, Tomas
dc.contributor.authorBriones, Juan
dc.contributor.authorAcevedo, Francisco
dc.date.accessioned2025-01-23T19:46:16Z
dc.date.available2025-01-23T19:46:16Z
dc.date.issued2020
dc.description.abstractBackground: About 80% of breast cancer (BC) cases express estrogen receptor (ER), which has been correlated with good prognosis and response to estrogen deprivation Aim: To characterize ER positive advanced BC (ABC) patients treated at our institution assessing the impact of clinical presentation (stage IV, de novo disease at diagnosis versus systemic recurrence) and BC subtype on survival rates. Material and Methods: We evaluated 211 ER+ advanced BC (ABC) patients, treated between 1997 and 2017. Results: The median overall survival (OS) was 37 months. Median OS for the period 1997/2006 and 2007/2017 were 33 and 42 months, respectively (p = 0.47). Luminal A, ABC stage IV disease at diagnosis displayed better OS rates than Luminal B stage IV tumors (100 and 32 months respectively, p < 0.01). Conclusions: Clinical presentation (stage IV vs. systemic recurrence) and tumor subtype are key determinants of OS in ABC.
dc.description.funderFONDECYT
dc.fuente.origenWOS
dc.identifier.eissn0717-6163
dc.identifier.issn0034-9887
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/100284
dc.identifier.wosidWOS:000604270300001
dc.issue.numero9
dc.language.isoen
dc.pagina.final1238
dc.pagina.inicio1233
dc.revistaRevista medica de chile
dc.rightsacceso restringido
dc.subjectBreast Neoplasms
dc.subjectNeoplasm Metastasis
dc.subjectPrognosis
dc.subjectReceptors
dc.subjectEstrogen
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleSurvival rates of advanced estrogen-receptor positive breast cancer. Analysis of 211 cases
dc.typeartículo
dc.volumen148
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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