Emerging alternatives against<i> Clostridioides difficile</i> infection

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dc.contributor.authorRomero-Rodriguez, A.
dc.contributor.authorMartinez de la Pena, C.
dc.contributor.authorTroncoso-Cotal, S.
dc.contributor.authorGuzman, C.
dc.contributor.authorSanchez, S.
dc.date.accessioned2025-01-20T21:01:51Z
dc.date.available2025-01-20T21:01:51Z
dc.date.issued2022
dc.description.abstractClostridioides difficile infection (CDI) is a significant worry within healthcare institutions and the community. It is one of the leading agents causing severe diarrhea worldwide. Effective management is critical since the morbidity and mortality attributed to CDI have increased exponentially over the past 20 years. Currently, antibiotics are the standard treatment for primary C. difficile infection, but at the same time, they are associated with disease relapse and increased drug resistance. CDI's high recurrence rates, spore generation, and antimicrobial resistance are currently significant challenges that urge the development of new options to combat this infection. This review describes up-and-coming alternatives and how they can mitigate the challenges associated with CDI. Here we have discussed the advantages and challenges of current and experimental alternatives against CDI. (C) 2022 Elsevier Ltd. All rights reserved.
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.anaerobe.2022.102638
dc.identifier.eissn1095-8274
dc.identifier.issn1075-9964
dc.identifier.urihttps://doi.org/10.1016/j.anaerobe.2022.102638
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/92968
dc.identifier.wosidWOS:000869733100003
dc.language.isoen
dc.revistaAnaerobe
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleEmerging alternatives against<i> Clostridioides difficile</i> infection
dc.typeartículo
dc.volumen78
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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