Earlier surgery is associated to re duce d postoperative morbidity in ileocaecal Crohn's disease: Results from SURGICROHN-LATAM study

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dc.contributor.authorAvellaneda, Nicolas
dc.contributor.authorCoy, Claudio Saddy Rodrigues
dc.contributor.authorFillmann, Henrique Sarubbi
dc.contributor.authorSaad-Hossne, Rogerio
dc.contributor.authorMunoz, Juan Pablo
dc.contributor.authorGarcia-Duperly, Rafael
dc.contributor.authorBellolio, Felipe
dc.contributor.authorRotholtz, Nicolas
dc.contributor.authorRossi, Gustavo
dc.contributor.authorMarquez, Juan Ricardo
dc.contributor.authorCillo, Mariano
dc.contributor.authorLacerda-Filho, Antonio
dc.contributor.authorCarrie, Augusto
dc.contributor.authorMaruyama, Beatriz Yuki
dc.contributor.authorFillmann, Lucio Sarubbi
dc.contributor.authorFerro, Ezequiel
dc.contributor.authorLondono-Schimmer, Eduardo
dc.contributor.authorIglesias, Andres
dc.contributor.authorHarriott, Camila Bras
dc.contributor.authorCampana, Juan Pablo
dc.contributor.authorEstrada, Daniel Londono
dc.contributor.authorBalachandran, Rogini
dc.contributor.authorKontze, Paulo Gustavo
dc.date.accessioned2025-01-20T20:11:28Z
dc.date.available2025-01-20T20:11:28Z
dc.date.issued2023
dc.description.abstractBackground: Early surgical resection is an emerging concept for patients with ileocaecal Crohn's disease (CD). The aim of this study was to compare postoperative outcomes after ileocaecal resections between patients with luminal and complicated CD.Methods: A retrospective analysis of patients operated for ileocaecal CD during an 8-year period in ten tertiary referral academic centres from Latin America was performed. Patients were allocated into 2 groups: those operated for early (luminal) disease (Early Crohn's Disease-ECD-) and for complications of CD (Complicated Crohn's disease-CCD-). A comparative analysis was performed regarding short-term outcomes of surgery, considering overall postoperative complications as main outcome. Results: 337 patients were included in the analysis, 60 (17.80%) in the ECD group. Smoking and ex-posure to perioperative biologic drugs were more prevalent in CCD group. CCD patients had increased requirement of urgent surgery (26.71 vs. 15%, p = 0.056), longer operative time (164.25 vs. 90.53 min, p < 0.01), lower rates of primary anastomosis (90.23 vs. 100%, p = 0.012), increased rate of overall postopera-tive complications (33.21 vs. 16.67%, p = 0.013), more reoperations (13.36 vs. 3.33%, p = 0.026), and higher rates of major anastomotic fistulas and hospital stay. On multivariable analysis, smoking ( p = 0.001,95%CI: 2.59-32.11), operative time ( p = 0.022,95%CI:1-1.02), associated procedures ( p = 0.036,95%CI:1.09-15.72) and intraoperative complications ( p = 0.021,95%CI:1.45-92.31) were independently related to presenting postoperative complications.
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.dld.2022.09.011
dc.identifier.eissn1878-3562
dc.identifier.issn1590-8658
dc.identifier.urihttps://doi.org/10.1016/j.dld.2022.09.011
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/92147
dc.identifier.wosidWOS:000992504800001
dc.issue.numero5
dc.language.isoen
dc.pagina.final594
dc.pagina.inicio589
dc.revistaDigestive and liver disease
dc.rightsacceso restringido
dc.subjectCrohn's disease
dc.subjectSurgery
dc.subjectColectomy
dc.subjectPostoperative complications
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleEarlier surgery is associated to re duce d postoperative morbidity in ileocaecal Crohn's disease: Results from SURGICROHN-LATAM study
dc.typeartículo
dc.volumen55
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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