A secondary focal segmental glomerulosclerosis due to prematurity

dc.contributor.authorValdes, Gloria
dc.contributor.authorNorero, Colomba
dc.contributor.authorMendez, Gonzalo P.
dc.date.accessioned2025-01-20T23:53:47Z
dc.date.available2025-01-20T23:53:47Z
dc.date.issued2021
dc.description.abstractBoth premature birth and low birth weight compromise nephron development. The lower nephron endowment is subjected to compensatory hyperfiltration that overloads the glomeruli and leads to the vicious circle of progressive deterioration of renal function. Objective: To emphasize the risk of renal involvement in this susceptible population by describing the case of a patient with long-term follow-up. Clinical Case: Low-weight premature newborn, who presented at 3 years of age severe hypertension, which was controlled with different types of antihypertensive drugs. However, 10 years later subnephrotic proteinuria was detected; a renal biopsy confirmed a focal and segmental glomerulosclerosis. Despite blocking the renin-angiotensin system for 23 years, his renal function progressively deteriorated, until requiring chronic hemodialysis during the last 3 years. Conclusion: It is essential to increase the awareness of the risk of renal damage in premature and low weight newborns in order to establish management that covers from gestation to adult life and to achieve an individual and epidemiological impact on renal health.
dc.fuente.origenWOS
dc.identifier.doi10.32641/andespediatr.v92i2.3013
dc.identifier.eissn2452-6053
dc.identifier.urihttps://doi.org/10.32641/andespediatr.v92i2.3013
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/94994
dc.identifier.wosidWOS:000808817300014
dc.issue.numero2
dc.language.isoen
dc.pagina.final267
dc.pagina.inicio263
dc.revistaAndes pediatrica
dc.rightsacceso restringido
dc.subjectPreterm Birth
dc.subjectLow Birth Weight
dc.subjectKidney Development
dc.subjectOligonephronia
dc.subjectFocal Segmental Glomerulosclerosis
dc.subjectRenal Failure
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleA secondary focal segmental glomerulosclerosis due to prematurity
dc.typeartículo
dc.volumen92
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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