Condensed tannins from<i> Pinus</i><i> radiata</i> bark: Extraction and their nanoparticles preparation in water by green method

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dc.contributor.authorCabrera-Barjas, Gustavo
dc.contributor.authorButto-Miranda, Nicole
dc.contributor.authorNesic, Aleksandra
dc.contributor.authorMoncada-Basualto, Mauricio
dc.contributor.authorSegura, Rodrigo
dc.contributor.authorBravo-Arrepol, Gaston
dc.contributor.authorEscobar-Avello, Danilo
dc.contributor.authorMoeini, Arash
dc.contributor.authorRiquelme, Sebastian
dc.contributor.authorNeira-Carrillo, Andronico
dc.date.accessioned2025-01-20T16:10:19Z
dc.date.available2025-01-20T16:10:19Z
dc.date.issued2024
dc.description.abstractThis work reports for the first time the production of condensed tannin nanoparticles stable in water via modification with glycine betaine. Pine bark, as a byproduct from the paper industry, was used as a source of condensed tannins of high molecular weight. Different glycine betaine concentrations were tested to produce condensed tannin nanoparticles, and the obtained nanoparticles were subjected to several characterization techniques (Dynamic Light Scattering, Field emission scanning electron microscopy, Zeta potential, Fourier transform infrared spectroscopy-Attenuated total reflectance, thermogravimetric analysis). The results showed that the highest stability possessed nanoparticles with 40 wt% glycine betaine. The average particle size distribution evaluated by scanning microscopy was 124 nm. Besides, the glycine betaine-modified condensed tannin nanoparticles demonstrated higher thermal stability with the starting degradation temperature at 238 degrees C. Finally, obtained nanoparticles showed an antioxidant capacity of 34,209 +/- 2194 mu mol ET/100 g and low cytotoxicity towards healthy human cells, representing the high potential to be used as a carrier of active compounds in agriculture, food, drug and medical sector.
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.ijbiomac.2024.134598
dc.identifier.eissn1879-0003
dc.identifier.issn0141-8130
dc.identifier.urihttps://doi.org/10.1016/j.ijbiomac.2024.134598
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/90204
dc.identifier.wosidWOS:001297818900001
dc.language.isoen
dc.revistaInternational journal of biological macromolecules
dc.rightsacceso restringido
dc.subjectPine bark extracts
dc.subjectPolyflavonoids
dc.subjectCondensed tannin
dc.subjectNanoparticles
dc.subjectEPR antioxidant activity
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleCondensed tannins from<i> Pinus</i><i> radiata</i> bark: Extraction and their nanoparticles preparation in water by green method
dc.typeartículo
dc.volumen278
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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