Investigating How Age Affects Self-Perception and Voice Awareness in Parkinson's Disease

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dc.article.number121883S
dc.contributor.authorContreras-Ruston, Francisco
dc.contributor.authorArriagada-Concha, Héctor
dc.contributor.authorLagos Villaseca, Antonia Elisa
dc.contributor.authorRojas, Sandra
dc.contributor.authorNapolitano, Carla
dc.contributor.authorKotz, Sonja
dc.contributor.authorNavarra, Jordi
dc.date.accessioned2025-05-01T10:31:05Z
dc.date.available2025-05-01T10:31:05Z
dc.date.issued2025
dc.description.abstractObjective: Parkinson's disease (PD) presents with voice disturbances accompanied by sensory processing and awareness deficits. Sensory feedback from the voice, which is essential in speech production, is often impaired in individuals with PD (IwPD), potentially leading to such difficulties in the self-perception and awareness of voice disorder. However, aging naturally affects sensory and motor brain systems, including those involved in voice production; therefore, it remains unclear whether the combined effects of age and PD exacerbate deficits in voice self-perception and awareness deficit. This study explored how age and sensory feedback in IwPD interact and affect self-perception and awareness of voice changes. Patient-reported outcome measures (PROMs) specific to the voice may not be efficient enough to capture voice changes in IwPD. Methods: The study included three groups of similar ages: 27 IwPD (61-79 years), 25 individuals with general voice disorders (GVD, aged 57-83 years), and 28 healthy controls (HC, aged 60-80 years). Self-perception of the voice was assessed by three PROMs: the Voice Symptoms Scale, Voice Handicap Index-10, and Voice-Related Quality of Life. Voice loudness was recorded and analyzed using univariate comparisons between the PROM scores. Further, multivariate techniques, such as principal component analysis (PCA) and cluster analysis, were used to identify intergroup differences in voice quality and voice self-awareness. Results: The IwPD group showed lower self-perception and awareness of voice problems than the GVD and HC groups. Within the IwPD group, age did not show a significant impact on self-perception of voice and awareness. This group showed slightly higher PROM scores than the HCs. In contrast, the GVD group showed marked differences in all PROMs and voice parameters compared with the HC and PD groups. PCA revealed significant differences in total scores and voice loudness between the groups. Conclusions: These findings suggest that age-related changes in sensory feedback are not significant factors affecting reduced self-perception and awareness of voice changes in IwPD. PCA and cluster analysis revealed distinct patterns among the groups, with GVD forming a separate cluster and IwPD displaying variability, partially overlapping with HC and GVD. This variability underscores the limited diagnostic utility of PROMs used to identify voice problems in IwPD compared with older individuals without PD, who generally exhibit greater awareness of voice disorders. Future studies should focus on developing tailored PROMs to better capture these challenges in IwPD.
dc.description.funderRed de Salud UC-Christus
dc.description.funderAgencia Chilena de Investigación y Desarrollo
dc.description.funderUniversity of San Sebastian
dc.description.funderBeca Chile para Estudios en el Extranjero 2020
dc.description.funderGeneralitat de Catalunya
dc.format.extent328 páginas
dc.fuente.origenScopus
dc.identifier.doi10.1016/j.jvoice.2025.02.032
dc.identifier.eisbn9781510653573
dc.identifier.eissn1660-4601
dc.identifier.issn0892-1997
dc.identifier.pubmedid35994695
dc.identifier.scieloidS0718-69242020000300109
dc.identifier.scopusidSCOPUS_ID:86000526698
dc.identifier.urihttps://doi.org/10.1016/j.jvoice.2025.02.032
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/103708
dc.identifier.wosidWOS:000894069600024
dc.information.autorucEscuela de Medicina; Lagos Villaseca, Antonia Elisa; 0000-0002-2579-5474; 185024
dc.issue.numero24
dc.language.isoen
dc.nota.accesoContenido parcial
dc.pagina.final378
dc.pagina.inicio357
dc.relation.ispartofJCO global oncology
dc.revistaJournal of Voice
dc.rightsacceso restringido
dc.subjectpublic health
dc.subjectChile
dc.subjectdemocracy
dc.subjectcivil participation
dc.subjectreform
dc.subjectqualitative research
dc.subjectLatin America
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titleInvestigating How Age Affects Self-Perception and Voice Awareness in Parkinson's Disease
dc.typeartículo
dc.volumen12
sipa.codpersvinculados185024
sipa.indexScopus
sipa.trazabilidadCarga WOS-SCOPUS;01-05-2025
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