Improvement of survival in infants with congenital diaphragmatic hernia in recent years: effect of ECMO availability and associated factors

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dc.contributor.authorKattan, Javier
dc.contributor.authorGodoy, Loreto
dc.contributor.authorZavala, Alejandro
dc.contributor.authorFaunes, Miriam
dc.contributor.authorBecker, Pedro
dc.contributor.authorEstay, Alberto
dc.contributor.authorFabres, Jorge
dc.contributor.authorToso, Paulina
dc.contributor.authorUrzua, Soledad
dc.contributor.authorBecker, Jorge
dc.contributor.authorCerda, Jaime
dc.contributor.authorGonzalez, Alvaro
dc.date.accessioned2025-01-21T00:05:31Z
dc.date.available2025-01-21T00:05:31Z
dc.date.issued2010
dc.description.abstractSurvival of patients with congenital diaphragmatic hernia (CDH) depends both on non-modifiable congenital conditions and on modifiable pre and postnatal management. ECMO improves survival up to 80% in neonates with CDH in the best ECMO centers worldwide. The first Neonatal ECMO Program in Chile was started in our University in 2003. Our objective is to determine the impact of a Neonatal ECMO Program in a level III NICU on newborns with CDH.
dc.description.abstractData of all newborns with CDH admitted to our NICU was separated into two groups: pre ECMO (1996-2003) and ECMO (2003-2007). Crude and adjusted odds ratios for 24 months survival were estimated by logistic regression.
dc.description.abstractData of 46 newborns with CDH was analysed, 20 in the pre ECMO and 26 in the ECMO period. Patient characteristics were similar in both groups; however, 24-month survival increased significantly from 25% (5/20) in the pre ECMO period to 77% (20/26) in the ECMO period (P = 0.001). Adjusted odds ratios for 24-month survival were 26.98 for OI a parts per thousand currency sign 40, 7.58 for 5 min Apgar a parts per thousand yen 7 and 17.5 for ECMO availability.
dc.description.abstractThe establishment of an ECMO program was associated with a significant increase in long-term survival for infants with CDH.
dc.fuente.origenWOS
dc.identifier.doi10.1007/s00383-010-2624-3
dc.identifier.eissn1437-9813
dc.identifier.issn0179-0358
dc.identifier.urihttps://doi.org/10.1007/s00383-010-2624-3
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/95551
dc.identifier.wosidWOS:000278952800003
dc.issue.numero7
dc.language.isoen
dc.pagina.final676
dc.pagina.inicio671
dc.revistaPediatric surgery international
dc.rightsacceso restringido
dc.subjectCongenital diaphragmatic hernia
dc.subjectCDH
dc.subjectExtracorporeal membrane oxygenation
dc.subjectECMO
dc.subjectELSO
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleImprovement of survival in infants with congenital diaphragmatic hernia in recent years: effect of ECMO availability and associated factors
dc.typeartículo
dc.volumen26
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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