RAT STRIATAL DOPAMINE AND TETRAHYDROBIOPTERIN CONTENT FOLLOWING AN INTRASTRIATAL INJECTION OF MANGANESE CHLORIDE

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dc.contributor.authorLISTA, A
dc.contributor.authorABARCA, J
dc.contributor.authorRAMOS, C
dc.contributor.authorDANIELS, AJ
dc.date.accessioned2025-01-23T19:26:26Z
dc.date.available2025-01-23T19:26:26Z
dc.date.issued1986
dc.description.abstractInjection of manganese into the rat corpus striatum causes a rapid fall in the biopterin and dopamine (DA) content ipsilateral to the lesion. Two weeks after the lesion both biopterin and DA are partially recovered. Controls, injected with saline or magnesium, do not show alterations in their DA or cofactor levels. It is proposed that the fall in DA levels results from a rapid displacement of the amine from its storage sites by manganese followed by a decrease in the rate of DA synthesis causes by the drop in cofactor levels.
dc.fuente.origenWOS
dc.identifier.eissn1879-0631
dc.identifier.issn0024-3205
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/99608
dc.identifier.wosidWOS:A1986C376600007
dc.issue.numero23
dc.language.isoen
dc.pagina.final2127
dc.pagina.inicio2121
dc.revistaLife sciences
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleRAT STRIATAL DOPAMINE AND TETRAHYDROBIOPTERIN CONTENT FOLLOWING AN INTRASTRIATAL INJECTION OF MANGANESE CHLORIDE
dc.typeartículo
dc.volumen38
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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