Paranasal sinuses computed tomography in the initial evaluation of patients with suspected invasive fungal rhinosinusitis

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dc.contributor.authorFinkelstein, Andres
dc.contributor.authorContreras, Daniela
dc.contributor.authorPardo, Javiera
dc.contributor.authorCruz, Juan P.
dc.contributor.authorGonzalez, Claudia
dc.contributor.authorBeltran, M. Constanza
dc.contributor.authorFonseca, Ximena
dc.date.accessioned2025-01-21T00:01:02Z
dc.date.available2025-01-21T00:01:02Z
dc.date.issued2011
dc.description.abstractInvasive fungal rhinosinusitis (IFR) is a complication that presents mainly in immunocompromised patients. Paranasal sinuses computed tomography (PCT) is frequently obtained during initial evaluation of suspected cases. The objective of the study was to determine the imaging findings that suggest IFR in patients with hematological malignancies. In the retrospective case/control study, we included 14 patients with hematological malignancies that developed IFR in the Hospital Clinico de la Pontificia Universidad Catolica de Chile between January 2005 and June 2009. Twenty patients with hematological malignancies, with suspected sinonasal infectious involvement requiring a PCT for initial evaluation, were chosen as the control group. Thirteen imaging parameters were compared between both groups. Osseous erosion and facial soft tissue thickening were statistically associated with the presence of IFR (p < 0.05). The presence of osseous erosion, facial soft tissue thickening, extrasinus extension or unilateral involvement had a positive predictive value of 100%, with an incidence among the total group of 12, 15, 9 and 9%, respectively. No patients with IFR had a normal PCT. Most PCTs in the initial evaluation of suspected IFR had nonspecific findings. The clinician must have a high index of suspicion and complement the workup with other diagnostic techniques to initiate appropriate treatment.
dc.fuente.origenWOS
dc.identifier.doi10.1007/s00405-011-1561-7
dc.identifier.eissn1434-4726
dc.identifier.issn0937-4477
dc.identifier.urihttps://doi.org/10.1007/s00405-011-1561-7
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/95369
dc.identifier.wosidWOS:000293555400010
dc.issue.numero8
dc.language.isoen
dc.pagina.final1162
dc.pagina.inicio1157
dc.revistaEuropean archives of oto-rhino-laryngology
dc.rightsacceso restringido
dc.subjectAspergillosis
dc.subjectMucormycosis
dc.subjectTomography scanners
dc.subjectX-ray computed
dc.subjectSinusitis
dc.subjectMycoses
dc.subjectHematologic neoplasms
dc.subjectImmunocompromised host
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleParanasal sinuses computed tomography in the initial evaluation of patients with suspected invasive fungal rhinosinusitis
dc.typeartículo
dc.volumen268
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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