Riboflavin Surface Modification of Poly(vinyl chloride) for Light-Triggered Control of Bacterial Biofilm and Virus Inactivation

Simple item page
dc.contributor.authorMunoz, Marcelo
dc.contributor.authorEl-Khoury, Antony
dc.contributor.authorCimenci, Cagla Eren
dc.contributor.authorGonzalez-Gomez, Mayte
dc.contributor.authorHunter, Robert A.
dc.contributor.authorLomboni, David
dc.contributor.authorVariola, Fabio
dc.contributor.authorRotstein, Benjamin H.
dc.contributor.authorVono, Lucas L. R.
dc.contributor.authorRossi, Liane M.
dc.contributor.authorMaria Edwards, Ana
dc.contributor.authorAlarcon, Emilio, I
dc.date.accessioned2025-01-20T22:14:09Z
dc.date.available2025-01-20T22:14:09Z
dc.date.issued2021
dc.description.abstractPoly(vinyl chloride) (PVC) is the most used biomedical polymer worldwide. PVC is a stable and chemically inert polymer. However, microorganisms can colonize PVC producing biomedical device-associated infections. While surface modifications of PVC can help improve the antimicrobial and antiviral properties, the chemically inert nature of PVC makes those modifications challenging and potentially toxic. In this work, we modified the PVC surface using a derivative riboflavin molecule that was chemically tethered to a plasma-treated PVC surface. Upon a low dosage of blue light, the riboflavin tethered to the PVC surface became photochemically activated, allowing for Pseudomonas aeruginosa bacterial biofilm and lentiviral in situ eradication.
dc.fuente.origenWOS
dc.identifier.doi10.1021/acsami.1c08042
dc.identifier.eissn1944-8252
dc.identifier.issn1944-8244
dc.identifier.urihttps://doi.org/10.1021/acsami.1c08042
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/94471
dc.identifier.wosidWOS:000674333400091
dc.issue.numero27
dc.language.isoen
dc.pagina.final32262
dc.pagina.inicio32251
dc.revistaAcs applied materials & interfaces
dc.rightsacceso restringido
dc.subjectPVC
dc.subjectsurface treatment
dc.subjectriboflavin
dc.subjectlight-activated materials
dc.subjectmedical polymers
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleRiboflavin Surface Modification of Poly(vinyl chloride) for Light-Triggered Control of Bacterial Biofilm and Virus Inactivation
dc.typeartículo
dc.volumen13
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
Files
Collections
Artículos de revistas