The impact of hypoglycemia on healthcare costs: a modeling study from Chile

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dc.contributor.authorBalmaceda, Carlos
dc.contributor.authorEspinoza, Manuel A.
dc.contributor.authorCabieses, Baltica
dc.contributor.authorEspinoza, Nazareth
dc.date.accessioned2025-01-20T22:02:09Z
dc.date.available2025-01-20T22:02:09Z
dc.date.issued2022
dc.description.abstractBackground: This study aimed to estimate the expected cost of hypoglycemia in Diabetes Mellitus type-2 patients receiving hypoglycemic treatment in Chile and to explore the effect of the potential reduction of hypoglycemia over the total cost incurred by its public health system.
dc.description.abstractResearch design and methods: A cost analysis was carried out based on a state transition mathematical model. The model used microsimulation with data from the National Health Survey 2016-2017 in Chile. Costs included follow-up, in-hospital and ambulatory care. Separate analysis was conducted for patients treated with insulin, or sulfonylurea.
dc.description.abstractResults: The annual expected total cost of hypoglycemia estimated for the Chilean public system was USD 288,922,523 (USD 273 per patient). The subgroup treated with insulin reached USD 353 per patient whereas the sulfonylurea subgroup was USD 217 per patient. The analysis revealed that for every 1% reduction of the incidence rate of severe hypoglycemia the cost is reduced 0.79% in total, 0.59% for the insulin subgroup, and 0.95% for the sulfonylurea subgroup.
dc.description.abstractConclusions: The cost of hypoglycemia represents a high proportion of the public health budget in Chile, being similar to those resources allocated to provide coverage of diabetic treatments through its universal health benefit plan.
dc.description.funderNovo Nordisk Chile
dc.fuente.origenWOS
dc.identifier.doi10.1080/14737167.2021.1865808
dc.identifier.eissn1744-8379
dc.identifier.issn1473-7167
dc.identifier.urihttps://doi.org/10.1080/14737167.2021.1865808
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/93940
dc.identifier.wosidWOS:000603997400001
dc.issue.numero1
dc.language.isoen
dc.pagina.final106
dc.pagina.inicio101
dc.revistaExpert review of pharmacoeconomics & outcomes research
dc.rightsacceso restringido
dc.subjectType 2 diabetes
dc.subjectcost analysis
dc.subjecthypoglycemia
dc.subjectchile
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleThe impact of hypoglycemia on healthcare costs: a modeling study from Chile
dc.typeartículo
dc.volumen22
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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