A new physiopathological classification of diabetic neuropathy

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dc.contributor.authorOlmos, Pablo R.
dc.contributor.authorNiklitschek, Sergio
dc.contributor.authorOlmos, Roberto I.
dc.contributor.authorFaundez, Jorge I.
dc.contributor.authorQuezada, Thomas A.
dc.contributor.authorBozinovic, Milan A.
dc.contributor.authorNiklitscheka, Ian A.
dc.contributor.authorAcosta, Jorge
dc.contributor.authorValencia, Claudio N.
dc.contributor.authorBravo, Felipe A.
dc.date.accessioned2024-01-10T13:45:50Z
dc.date.available2024-01-10T13:45:50Z
dc.date.issued2012
dc.description.abstractNowadays, Diabetic Neuropathy (DN) is considered the most common cause of peripheral neuropathy in clinical practice. It can affect sensitive, motor or autonomic nerve fibers, with symmetric, asymmetric, acute or chronic presentations. Due to this variability, with multiple physiopathologic mechanisms involved, a complex clinical classification has been used until recently. The aim of this review is to present a new classification of diabetic neuropathy, based on its physiopathology. It is divided in metabolic microvascular and hypoxic, autoimmune and inflammatory, compressive, secondary to complications of diabetes and related to treatment. It must be understood that DN is not just a functional disease, but a complication of diabetes with molecular and pathological substrates caused by hyperglycemia. Therefore, normalization of blood glucose is a fundamental step towards the successful prevention and treatment of DN. (Rev Med Chile 2012; 140: 1593-1605).
dc.fechaingreso.objetodigital2024-05-29
dc.format.extent13 páginas
dc.fuente.origenWOS
dc.identifier.doi10.4067/S0034-98872012001200012
dc.identifier.eissn0717-6163
dc.identifier.issn0034-9887
dc.identifier.pubmedidMEDLINE:23677234
dc.identifier.urihttps://doi.org/10.4067/S0034-98872012001200012
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/79087
dc.identifier.wosidWOS:000314435000012
dc.information.autorucMedicina;Acosta J ;S/I;149116
dc.information.autorucMedicina;Bozinovic M;S/I;163778
dc.information.autorucMedicina;Faundez J;S/I;195749
dc.information.autorucMedicina;Niklitschek S ;S/I;156246
dc.information.autorucMedicina;Niklitscheka I;S/I;187211
dc.information.autorucIngeniería;Olmos P;S/I;98949
dc.information.autorucMedicina;Olmos R;S/I;163754
dc.information.autorucMedicina;Quezada T;S/I;186145
dc.information.autorucMedicina;Valencia C;S/I;142539
dc.issue.numero12
dc.language.isoes
dc.nota.accesoContenido completo
dc.pagina.final1605
dc.pagina.inicio1593
dc.publisherSOC MEDICA SANTIAGO
dc.revistaREVISTA MEDICA DE CHILE
dc.rightsacceso abierto
dc.subjectDiabetes complications
dc.subjectDiabetic neuropathies
dc.subjectPhysiopathology
dc.subjectADVANCED GLYCATION ENDPRODUCTS
dc.subjectGLUCOSE-METABOLISM
dc.subjectTHIAMINE
dc.subjectINSULIN
dc.subjectMANAGEMENT
dc.subjectRELEVANCE
dc.subjectMELLITUS
dc.subjectRECEPTOR
dc.subjectRAGE
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleA new physiopathological classification of diabetic neuropathy
dc.typeartículo
dc.volumen140
sipa.codpersvinculados149116
sipa.codpersvinculados163778
sipa.codpersvinculados195749
sipa.codpersvinculados156246
sipa.codpersvinculados187211
sipa.codpersvinculados98949
sipa.codpersvinculados163754
sipa.codpersvinculados186145
sipa.codpersvinculados142539
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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