RENIN-SECRETING TUMOR - CASE-REPORT

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dc.contributor.authorVALDES, G
dc.contributor.authorLOPEZ, JM
dc.contributor.authorMARTINEZ, P
dc.contributor.authorROSENBERG, H
dc.contributor.authorBARRIGA, P
dc.contributor.authorRODRIGUEZ, JA
dc.contributor.authorOTIPKA, N
dc.date.accessioned2025-01-23T19:44:25Z
dc.date.available2025-01-23T19:44:25Z
dc.date.issued1980
dc.description.abstractRenin-secreting tumor, though rare, should be considered in assessing severe hyperreninemic, hypertensive patients. An 18-yr-old girl with hypokalemic hyperreninemic hyperaldosteronism was studied. No angiographic lesion was detected. The plasma renin activity (PRA) of the right/left renal vein was 7.3. With a presumptive diagnosis of renin-secreting tumor (RST), the patient was operated on, and a cortical nodule was found on the right lower pole. Partial nephrectomy was followed by a rapid fall in PRA (half-life, 33-44 min) and normalization of blood pressure (BP). At 3 1/2 mo. postoperatively, the patient showed normotension, normopokalemia, normal aldosterone and slightly elevated PRA unresponsive to postural changes and furosemide treatment. Tumoral PRA secretion responded to postural stimulus, spironolactone use and nitroprusside-induced hypotension. Neither the high aldosterone excretion nor hyperreninemia decreased after 3 days of DOCA [deoxycorticosterone acetate]; this agrees with a previously reported case, suggesting the usefulness of this test in the diagnosis of RST.
dc.fuente.origenWOS
dc.identifier.eissn1524-4563
dc.identifier.issn0194-911X
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/100034
dc.identifier.wosidWOS:A1980KH87900017
dc.issue.numero5
dc.language.isoen
dc.pagina.final718
dc.pagina.inicio714
dc.revistaHypertension
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleRENIN-SECRETING TUMOR - CASE-REPORT
dc.typeartículo
dc.volumen2
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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