Risk factors for major complications after surgical treatment of primary ileocecal Crohn's disease. A multicenter Latin American experience

dc.contributor.authorAvellaneda, Nicolas
dc.contributor.authorCoy, Claudio Saddy Rodrigues
dc.contributor.authorFillmann, Henrique Sarubbi
dc.contributor.authorSaad-hossne, Rogerio
dc.contributor.authorMun, Juan Pablo
dc.contributor.authorGarcia-duperly, Rafael
dc.contributor.authorBellolio, Felipe
dc.contributor.authorRotholtz, Nicolas
dc.contributor.authorRossi, Gustavo
dc.contributor.authorMarquez, Juan Ricardo
dc.contributor.authorCillo, Mariano
dc.contributor.authorLacerda-filho, Antonio
dc.contributor.authorCarrie, Augusto
dc.contributor.authorMaruyama, Beatriz Yuki
dc.contributor.authorFillmann, Lucio Sarubbi
dc.contributor.authorCraveiro, Marcela Maria Silvino
dc.contributor.authorFerro, Ezequiel
dc.contributor.authorLondono-schimmer, Eduardo
dc.contributor.authorIglesias, Andres
dc.contributor.authorHarriott, Camila Bras
dc.contributor.authorCampana, Juan Pablo
dc.contributor.authorEstrada, Daniel London
dc.contributor.authorBalachandran, Rogini
dc.contributor.authorKotze, Paulo Gustavo
dc.date.accessioned2025-01-20T17:19:56Z
dc.date.available2025-01-20T17:19:56Z
dc.date.issued2023
dc.description.abstractIntroduction: Complications after ileocecal resection for Crohn's disease (CD) are frequent. The aim of this study was to analyze risk factors for postoperative complications after these procedures.
dc.description.abstractMaterials and methods: We conducted a retrospective analysis of patients treated surgically for Crohn's disease limited to the ileocecal region during an 8-year period at 10 medical centers specialized in inflammatory bowel disease (IBD) in Latin America. Patients were allocated into 2 groups: those who presented major postoperative complications (Clavien-Dindo > II), the "postoperative complication" (POC) group; and those who did not, the "no postoperative complication" (NPOC) group. Preoperative characteristics and intraoperative variables were analyzed to identify possible factors for POC.
dc.description.abstractResults: In total, 337 patients were included, with 51 (15.13%) in the POC cohort. Smoking was more prevalent among the POC patients (31.37 vs. 17.83; P = .026), who presented more preoperative anemia (33.33 vs. 17.48%; P = .009), required more urgent care (37.25 vs. 22.38; P = .023), and had lower albumin levels. Complicated disease was associated with higher postoperative morbidity. POC patients had a longer operative time (188.77 vs. 143.86 min; P = .005), more intraoperative complications (17.65 vs. 4.55%; P < .001), and lower rates of primary anastomosis. In the multivariate analysis, both smoking and intraoperative complications were independently associated with the occurrence of major postoperative complications.
dc.description.abstractConclusion: This study shows that risk factors for complications after primary ileocecal resections for Crohn's disease in Latin America are similar to those reported elsewhere. Future efforts in the region should be aimed at improving these outcomes by controlling some of the identified factors. (c) 2023AEC. Published by Elsevier Espana, S.L.U. All rights reserved.
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.ciresp.2023.04.001
dc.identifier.eissn1578-147X
dc.identifier.issn0009-739X
dc.identifier.urihttps://doi.org/10.1016/j.ciresp.2023.04.001
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/91413
dc.identifier.wosidWOS:001127789200001
dc.issue.numero12
dc.language.isoen
dc.pagina.final832
dc.pagina.inicio824
dc.revistaCirugia espanola
dc.rightsacceso restringido
dc.subjectCrohn
dc.subjectIleocecal
dc.subjectResection
dc.subjectIBD
dc.subjectRisk
dc.subjectComplication
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleRisk factors for major complications after surgical treatment of primary ileocecal Crohn's disease. A multicenter Latin American experience
dc.typeartículo
dc.volumen101
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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