Acute liver failure and liver transplantation secondary to flutamide treatment in a prostate cancer patient

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dc.contributor.authorRojas, Pablo A.
dc.contributor.authorIglesias, Tomas G.
dc.contributor.authorBarrera Martínez, Francisco
dc.contributor.authorMendez, Gonzalo P.
dc.contributor.authorTorres, Javiera
dc.contributor.authorSan Francisco, Ignacio F.
dc.date.accessioned2025-01-23T19:47:20Z
dc.date.available2025-01-23T19:47:20Z
dc.date.issued2020
dc.description.abstractFlutamide is a first-generation nonsteroidal antiandrogen, used for treatment of advanced prostate cancer (PCa). We present the clinical case of a patient with localized high-risk PCa who started flutamide before radical prostatectomy and evolved with acute liver failure and liver transplantation. Hepatotoxicity induced by antiandrogen therapy, and current indications for first generation anti-androgen therapy were reviewed. To our knowledge, this is the first report of a man diagnosed with PCa who evolved with acute liver failure secondary to flutamide, and finally required liver transplantation.
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.eucr.2020.101370
dc.identifier.eissn2214-4420
dc.identifier.urihttps://doi.org/10.1016/j.eucr.2020.101370
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/100373
dc.identifier.wosidWOS:000580413800109
dc.information.autorucEscuela de Medicina; Barrera Martínez, Francisco; 0000-0001-5334-1528; 14816
dc.language.isoen
dc.revistaUrology case reports
dc.rightsacceso restringido
dc.subjectAcute liver failure
dc.subjectAnti-androgen therapy
dc.subjectFlutamide
dc.subjectProstate cancer
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleAcute liver failure and liver transplantation secondary to flutamide treatment in a prostate cancer patient
dc.typeartículo
dc.volumen33
sipa.codpersvinculados14816
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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