Dermoscopy as a clinical tool for the diagnosis of demodicosis: a retrospective intrapatient case-control study

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dc.contributor.authorParra-Cares, Julio
dc.contributor.authorMeza-Romero, Rodrigo
dc.contributor.authorIbanez, Samuel
dc.contributor.authorCanales, Marilena
dc.contributor.authorConcha, Monica
dc.contributor.authorNavarrete-Dechent, Cristian
dc.contributor.authorAbarzua-Araya, Alvaro
dc.date.accessioned2025-01-20T16:11:09Z
dc.date.available2025-01-20T16:11:09Z
dc.date.issued2024
dc.description.abstractDermoscopy has been used for the non-invasive diagnosis of demodicosis. Several studies have evaluated the usefulness of this tool in the diagnosis, however, there are differences in the gold standard (SSSB or KOH test) and criteria of positivity used between studies. Added to this, is the lack of controls and objective quantification of the usefulness of dermoscopic signs in clinically observable and relevant ranges. To validate the usefulness of dermoscopy for the diagnosis of demodicosis by calculating the performance indicators for the different dermoscopic signs. Retrospective intrapatient case-control study, which included adults with suspicion of demodicosis. Dermoscopic photographs and scraping of healthy and lesional skin were obtained. Samples were analyzed microscopically by trained personnel. Photographs were evaluated by determining the presence of Demodex tails (DT), dilated follicular openings (DFO) and dilated blood vessels (DBV) in pre-defined ranges. 64 patients were included (total = 256 samples); the presence of demodex on skin scraping was seen in 69%. Under dermoscopy, the presence of DT in range 11-20/field had a positive likelihood ratio (LR) of 12.10 (95%CI 6.52-22.45) and negative LR 0.32 (95%CI 0.23-0.45). Combined and dichotomized performance for at least one positive sign under dermoscopy (DT > 10/field, DFO > 10/field or DBV > 50% of the field): positive LR 7.14 (95%CI 4.80-10.62) and negative LR 0.11 (95%CI 0.06-0.22). The presence of DT, DFO or DBV has a high correlation with a positive mite test, so the diagnosis of demodicosis could be made only through dermoscopy.
dc.description.funderResident projects year 2019", Research Directorate, Faculty of Medicine, Pontificia Universidad Catolica de Chile, Santiago de Chile, Chile
dc.fuente.origenWOS
dc.identifier.doi10.1007/s00403-024-03252-1
dc.identifier.eissn1432-069X
dc.identifier.issn0340-3696
dc.identifier.urihttps://doi.org/10.1007/s00403-024-03252-1
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/90253
dc.identifier.wosidWOS:001288498100001
dc.issue.numero8
dc.language.isoen
dc.revistaArchives of dermatological research
dc.rightsacceso restringido
dc.subjectDemodicosis
dc.subjectDemodex folliculorum
dc.subjectDemodex brevis
dc.subjectPityriasis folliculorum
dc.subjectDermoscopy
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleDermoscopy as a clinical tool for the diagnosis of demodicosis: a retrospective intrapatient case-control study
dc.typeartículo
dc.volumen316
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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