Visual field progression in patients with severe glaucoma

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dc.contributor.authorMaul, Eugenio J.
dc.contributor.authorKastner, Alan
dc.contributor.authorSchmidt, Jimena
dc.contributor.authorTapia, Jaime A.
dc.contributor.authorMorales, Cristobal
dc.contributor.authorMaul, Eugenio A.
dc.date.accessioned2025-01-20T23:55:19Z
dc.date.available2025-01-20T23:55:19Z
dc.date.issued2021
dc.description.abstractPurpose To assess the cumulative risk of progression in glaucomatous eyes in the severe stage of disease. Methods This was a retrospective observational study. Patients that had severe damage in at least one eye, as defined by three criteria including a mean deviation of <= - 20 dB, were included. Glaucoma progression was defined as a loss of >= 2 dB in mean deviation confirmed in three consecutive visual field tests, or a persistent loss of two or more lines of vision-not attributable to non-glaucomatous causes-in three consecutive follow-up examinations. Kaplan-Meier survival analysis was used to assess the cumulative incidence of progression of the first eye to reach endpoint in cases where both eyes were eligible. Results A total of 143 eyes from 119 patients, were studied over a mean period of 4.9 +/- 2.9 years. Baseline mean deviation was - 25.3 +/- 3.6 dB. Twenty-three eyes of 22 patients reached the progression endpoint: 14 eyes by visual field criteria and 9 by visual acuity criteria. The cumulative 5-year risk of progression estimated by Kaplan-Meier analysis was 14.6% (95% confidence interval: 6.1-22.2%). Conclusions In severe glaucoma patients, we found a cumulative incidence of progression of 2.9% per year during the first 5 years of follow-up. Similar incidences have been reported in other studies of glaucoma at different stages of severity.
dc.fuente.origenWOS
dc.identifier.doi10.1007/s00417-020-05036-5
dc.identifier.eissn1435-702X
dc.identifier.issn0721-832X
dc.identifier.urihttps://doi.org/10.1007/s00417-020-05036-5
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/95080
dc.identifier.wosidWOS:000606211000005
dc.issue.numero6
dc.language.isoen
dc.pagina.final1586
dc.pagina.inicio1579
dc.revistaGraefes archive for clinical and experimental ophthalmology
dc.rightsacceso restringido
dc.subjectGlaucoma
dc.subjectHumphrey
dc.subjectVisual field damage
dc.subjectProgression
dc.subjectSevere
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleVisual field progression in patients with severe glaucoma
dc.typeartículo
dc.volumen259
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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