The case for simplifying and using absolute targets for viral hepatitis elimination goals

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dc.contributor.authorRazavi, Homie
dc.contributor.authorBlach, Sarah
dc.contributor.authorRazavi-Shearers, Devin
dc.contributor.authorAbaalkhail, Faisal
dc.contributor.authorAbbas, Zaigham
dc.contributor.authorAbdallah, Ayat
dc.contributor.authorFerreira, Paulo Abrao
dc.contributor.authorAbu Raddad, Laith Jamal
dc.contributor.authorAdda, Danjuma
dc.contributor.authorAgarwal, Kosh
dc.contributor.authorAghemo, Alessio
dc.contributor.authorAhmed, Aijaz
dc.contributor.authorAl-Busafi, Said A.
dc.contributor.authorAl-hamoudi, Waleed
dc.contributor.authorAl-Kaabi, Saad
dc.contributor.authorAl-Romaihi, Hamad
dc.contributor.authorAljarallah, Badr
dc.contributor.authorAlNaamani, Khalid
dc.contributor.authorAlqahtani, Saleh
dc.contributor.authorAlswat, Khalid
dc.contributor.authorAltraif, Ibrahim
dc.contributor.authorAsselah, Tarik
dc.contributor.authorBacon, Bruce
dc.contributor.authorBessone, Fernando
dc.contributor.authorBizri, Abdul Rahman
dc.contributor.authorBlock, Tim
dc.contributor.authorBonino, Ferruccio
dc.contributor.authorBranclaoMello, Carlos Eduardo
dc.contributor.authorBrowny, Kimberly
dc.contributor.authorBruggmann, Philip
dc.contributor.authorBrunetto, Maurizia Rossana
dc.contributor.authorButi, Maria
dc.contributor.authorCabezas, Joaquin
dc.contributor.authorCalleja, Jose Luis
dc.contributor.authorBatanjer, Erika Castro
dc.contributor.authorChan, Henry Lik-Yuen
dc.contributor.authorChang, Henry
dc.contributor.authorChen, Chien-Jen
dc.contributor.authorChristensen, Peer Brehm
dc.contributor.authorChuang, Wan-Long
dc.contributor.authorCisneros, Laura
dc.contributor.authorCohen, Chari
dc.contributor.authorColombo, Massimo
dc.contributor.authorConway, Brian
dc.contributor.authorCooper, Curtis
dc.contributor.authorCraxi, Antonio
dc.contributor.authorCrespo, Javier
dc.contributor.authorCroes, Esther
dc.contributor.authorCryer, Donna
dc.contributor.authorde Barros, Fernando Passos Cupertino
dc.contributor.authorDerbala, Moutaz
dc.contributor.authorDillon, John
dc.contributor.authorDoss, Wahid
dc.contributor.authorDou, Xiaoguang
dc.contributor.authorDoyle, Joseph
dc.contributor.authorDuberg, Ann-Sofi
dc.contributor.authorDugan, Ellen
dc.contributor.authorDunn, Rick
dc.contributor.authorDusheiko, Geoffrey
dc.contributor.authorEl Khayat, Hisham
dc.contributor.authorEI-Sayed, Manal H.
dc.contributor.authorEshraghian, Ahad
dc.contributor.authorEsmat, Gamal
dc.contributor.authorMur, Rafael Esteban
dc.contributor.authorEzzat, Sameera
dc.contributor.authorFalconer, Karolin
dc.contributor.authorFassio, Eduardo
dc.contributor.authorFerrinho, Paulo
dc.contributor.authorFlamm, Steven
dc.contributor.authorFlisiak, Robert
dc.contributor.authorFoster, Graham
dc.contributor.authorFung, James
dc.contributor.authorGarcia-Samaniego, Javier
dc.contributor.authorGish, Robert G.
dc.contributor.authorGoncales, Fernando
dc.contributor.authorHalota, Waldemar
dc.contributor.authorHamoudi, Waseem
dc.contributor.authorHassany, Mohamed
dc.contributor.authorHatzakis, Angelos
dc.contributor.authorHay, Susan
dc.contributor.authorHimatt, Sayed
dc.contributor.authorHoepelman, I. M.
dc.contributor.authorHsu, Yao-Chun
dc.contributor.authorHui, Yee Tak
dc.contributor.authorHunyady, Bela
dc.contributor.authorJacobson, Ira
dc.contributor.authorJanjua, Naveed
dc.contributor.authorJanssen, Harry
dc.contributor.authorJarcuska, Peter
dc.contributor.authorKabagambe, Kenneth
dc.contributor.authorKanto, Tatsuya
dc.contributor.authorKao, Jia-Horng
dc.contributor.authorKaymakoglu, Sabahattin
dc.contributor.authorKershenobich, David
dc.contributor.authorKhamis, Faryal
dc.contributor.authorKim, Dong Joon
dc.contributor.authorKim, Young
dc.contributor.authorKondili, Loreta A.
dc.contributor.authorKottiliI, Shyamasundaran
dc.contributor.authorKramvis, Anna
dc.contributor.authorKugelmas, Marcelo
dc.contributor.authorKurosaki, Masayuki
dc.contributor.authorLacombe, Karine
dc.contributor.authorLagging, Martin
dc.contributor.authorLao, WaiCheung
dc.contributor.authorLavanchy, Daniel
dc.contributor.authorLazarus, Jeffrey, V
dc.contributor.authorLee, Alice
dc.contributor.authorLee, Samual S.
dc.contributor.authorLevyl, Miriam
dc.contributor.authorLiakina, Valentina
dc.contributor.authorLim, YoungSuk
dc.contributor.authorLiu, Shuang
dc.contributor.authorMaddrey, Willis
dc.contributor.authorMalekzade, Reza
dc.contributor.authorMarinho, Rui Tato
dc.contributor.authorMathur, Poonam
dc.contributor.authorMaticic, Mojca
dc.contributor.authorMendes Correa, Maria Cassia
dc.contributor.authorMera, Jorge
dc.contributor.authorMerat, Shahin
dc.contributor.authorMogawer, Sherif
dc.contributor.authorMohamed, Rosmawati
dc.contributor.authorMuellhaupti, Beat
dc.contributor.authorMuljono, David
dc.contributor.authorMostafa, Ibrahim
dc.contributor.authorNahum, Mendez Sanchez
dc.contributor.authorNawaz, Arif
dc.contributor.authorNegro, Francesco
dc.contributor.authorNinburg, Michael
dc.contributor.authorNing, Qing
dc.contributor.authorNtiri-Reid, Boatemaa
dc.contributor.authorNymadawa, Pagbajabyn
dc.contributor.authorOevrehus, Anne
dc.contributor.authorOrmeci, Necati
dc.contributor.authorOrrego, Mauricio
dc.contributor.authorOsman, Alaa
dc.contributor.authorOyunsuren, Tsendsuren
dc.contributor.authorPant, Calvin
dc.contributor.authorPapaevangelou, Vassiliki
dc.contributor.authorPapatheodoridis, George
dc.contributor.authorPopping, Stephanie
dc.contributor.authorPrasad, Papu
dc.contributor.authorPrithiviputh, Rittoo
dc.contributor.authorQureshi, Huma
dc.contributor.authorRamji, Alnoor
dc.contributor.authorRazavi-Shearer, Kathryn
dc.contributor.authorReddy, Rajender
dc.contributor.authorRemak, William
dc.contributor.authorRichter, Clemens
dc.contributor.authorRidruejo, Ezequiel
dc.contributor.authorRobaeys, Geert
dc.contributor.authorRobert, Stuart
dc.contributor.authorRoberts, Lewis
dc.contributor.authorRoudot-Thoraval, Francoise
dc.contributor.authorSaab, Sammy
dc.contributor.authorSaid, Sanaa
dc.contributor.authorSalamat, Amjad
dc.contributor.authorSanai, Faisal
dc.contributor.authorSanchez-Avila, Juan Francisco
dc.contributor.authorSchiff, Eugene
dc.contributor.authorSchinazi, Raymond
dc.contributor.authorSebastiani, Giada
dc.contributor.authorSeguin-Devaux, Carole
dc.contributor.authorShanmugam, R. P.
dc.contributor.authorSharara, Ala
dc.contributor.authorShilton, Sonjelle
dc.contributor.authorShouval, Daniel
dc.contributor.authorSievert, William
dc.contributor.authorSimonova, Marieta
dc.contributor.authorSohrabpour, Amir Ali
dc.contributor.authorSonderup, Mark
dc.contributor.authorSoza, Alejandro
dc.contributor.authorSpearman, C. Wendy
dc.contributor.authorSteinfurth, Nancy
dc.contributor.authorSulkowski, Mark
dc.contributor.authorTan, Soek-Siam
dc.contributor.authorTanaka, Junko
dc.contributor.authorTashi, Dhondup
dc.contributor.authorThein, Hla-Hla
dc.contributor.authorThompson, Peyton
dc.contributor.authorTolmane, Ieva
dc.contributor.authorToy, Mehlika
dc.contributor.authorValantinas, Jonas
dc.contributor.authorVan de Vijver, David
dc.contributor.authorVelez-Moller, Patricia
dc.contributor.authorVince, Adriana
dc.contributor.authorWaked, Imam
dc.contributor.authorWang, Su
dc.contributor.authorWedemeyer, Heiner
dc.contributor.authorWong, Vincent
dc.contributor.authorXie, Qing
dc.contributor.authorYamada, Seiji
dc.contributor.authorYang, Hwai-, I
dc.contributor.authorYesmembetov, Kakharman
dc.contributor.authorYilmaz, Yusuf
dc.contributor.authorYounossi, Zobair
dc.contributor.authorYu, Ming-Lung
dc.contributor.authorYuen, Man-Fung
dc.contributor.authorYurdaydin, Cihan
dc.contributor.authorYusuf, Aasim
dc.contributor.authorZekry, Amany
dc.contributor.authorZeuzem, Stefan
dc.date.accessioned2025-01-20T23:56:05Z
dc.date.available2025-01-20T23:56:05Z
dc.date.issued2021
dc.description.abstractThe 69th World Health Assembly endorsed the Global Health Sector Strategy for Viral Hepatitis, embracing a goal to eliminate hepatitis infection as a public health threat by 2030. This was followed by the World Health Organization's (WHO) global targets for the care and management of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. These announcements and targets were important in raising awareness and calling for action; however, tracking countries' progress towards these elimination goals has provided insights to the limitations of these targets. The existing targets compare a country's progress relative to its 2015 values, penalizing countries who started their programmes prior to 2015, countries with a young population, or countries with a low prevalence. We recommend that (1) WHO simplify the hepatitis elimination targets, (2) change to absolute targets and (3) allow countries to achieve these disease targets with their own service coverage initiatives that will have the maximum impact. The recommended targets are as follows: reduce HCV new chronic cases to <= 5 per 100 000, reduce HBV prevalence among 1-year-olds to <= 0.1%, reduce HBV and HCV mortality to <= 5 per 100 000, and demonstrate HBV and HCV year-to-year decrease in new HCV- and HBV-related HCC cases. The objective of our recommendations is not to lower expectations or diminish the hepatitis elimination standards, but to provide clearer targets that recognize the past and current elimination efforts by countries, help measure progress towards true elimination, and motivate other countries to follow suit.
dc.description.funderJohn C Martin Foundation
dc.fuente.origenWOS
dc.identifier.doi10.1111/jvh.13412
dc.identifier.eissn1365-2893
dc.identifier.issn1352-0504
dc.identifier.urihttps://doi.org/10.1111/jvh.13412
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/95131
dc.identifier.wosidWOS:000584509000001
dc.issue.numero1
dc.language.isoen
dc.pagina.final19
dc.pagina.inicio12
dc.revistaJournal of viral hepatitis
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleThe case for simplifying and using absolute targets for viral hepatitis elimination goals
dc.typeartículo
dc.volumen28
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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