KALLIKREIN-KININ AND RENIN-ANGIOTENSIN SYSTEMS IN RENOVASCULAR HYPERTENSION IN RATS

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dc.contributor.authorVIO, CP
dc.contributor.authorROBLERO, JS
dc.contributor.authorCROXATTO, HR
dc.date.accessioned2025-01-23T19:44:33Z
dc.date.available2025-01-23T19:44:33Z
dc.date.issued1980
dc.description.abstractPlasma renin activity (PRA) and the levels of urinary kallikrein (UK) were studied simultaneously in Goldblatt 1- and 2-kidney hypertensive rats (1KG and 2KG) 5, 10 and 15 wk after clamping the left renal artery. Increase in PRA was statistically significant in 2KG rats (P < 0.0005 on the 5th and 10th wk, and P < 0.002 on the 15th wk). PRA was not significantly different to that of controls in 1KG rats. The urinary kallikrein levels were significantly lower in 1KG rats (P < 0.002) in relation to values found in normotensive rats. In 2KG rats, urinary kallikrein levels became significantly lower than those in controls only 15 wk after surgery.
dc.fuente.origenWOS
dc.identifier.issn0037-9727
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/100073
dc.identifier.wosidWOS:A1980JQ63200001
dc.issue.numero4
dc.language.isoen
dc.pagina.final451
dc.pagina.inicio447
dc.revistaProceedings of the society for experimental biology and medicine
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleKALLIKREIN-KININ AND RENIN-ANGIOTENSIN SYSTEMS IN RENOVASCULAR HYPERTENSION IN RATS
dc.typeartículo
dc.volumen163
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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