Chemical and botanical characterization of Chilean propolis and biological activity on cariogenic bacteria <i>Streptococcus</i> <i>mutans</i> and <i>Streptococcus</i> <i>sobrinus</i>

Simple item page
dc.contributor.authorBarrientos, Leticia
dc.contributor.authorHerrera, Christian L.
dc.contributor.authorMontenegro, Gloria
dc.contributor.authorOrtega, Ximena
dc.contributor.authorVeloz, Jorge
dc.contributor.authorAlvear, Marysol
dc.contributor.authorCuevas, Alejandro
dc.contributor.authorSaavedra, Nicolas
dc.contributor.authorSalazar, Luis A.
dc.date.accessioned2025-01-24T00:08:02Z
dc.date.available2025-01-24T00:08:02Z
dc.date.issued2013
dc.description.abstractPropolis is a non-toxic natural substance with multiple pharmacological properties including anticancer, antioxidant, fungicidal, antibacterial, antiviral, and anti-inflammatory among others. The aim of this study was to determine the chemical and botanical characterization of Chilean propolis samples and to evaluate their biological activity against the cariogenic bacteria Streptococcus mutans and Streptococcus sobrinus. Twenty propolis samples were obtained from beekeeping producers from the central and southern regions of Chile. The botanical profile was determined by palynological analysis. Total phenolic contents were determined using colorimetric assays. Reverse phase HPLC and HPLC-MS were used to determine the chemical composition. The minimum inhibitory concentration (MIC) was determined on S. mutans and S. sobrinus. All propolis samples were dominated by structures from native plant species. The characterization by HPLC/MS, evidenced the presence of quercetin, myricetin, kaempferol, rutine, pinocembrin, coumaric acid, caffeic acid and caffeic acid phenethyl ester, that have already been described in these propolis with conventional HPLC. Although all propolis samples inhibited the mutans streptococci growth, it was observed a wide spectrum of action (MIC 0.90 to 8.22 mu g mL(-1)). Given that results it becomes increasingly evident the need of standardization procedures, where we combine both the determination of botanical and the chemical characterization of the extracts. Research conducted to date, describes a promising effectiveness of propolis in the prevention of caries and other diseases of the oral cavity, making it necessary to develop studies to identify and understand the therapeutic targets or mechanisms of molecular action of the various compounds present on them.
dc.fuente.origenWOS
dc.identifier.eissn1678-4405
dc.identifier.issn1517-8382
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/101942
dc.identifier.wosidWOS:000325780000037
dc.issue.numero2
dc.language.isoen
dc.pagina.final585
dc.pagina.inicio577
dc.revistaBrazilian journal of microbiology
dc.rightsacceso restringido
dc.subjectpropolis
dc.subjectbotanical characterization
dc.subjectchemical characterization
dc.subjectStreptococcus mutans
dc.subjectStreptococcus sobrinus
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleChemical and botanical characterization of Chilean propolis and biological activity on cariogenic bacteria <i>Streptococcus</i> <i>mutans</i> and <i>Streptococcus</i> <i>sobrinus</i>
dc.typeartículo
dc.volumen44
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
Files
Collections
Artículos de revistas