<i>Helicobacter pylori</i> infection and UBT-<SUP>13</SUP>C values are associated with changes in body mass index in children and adults

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dc.contributor.authorBruera, Maria J.
dc.contributor.authorAmezquita, Maria V.
dc.contributor.authorRiquelme, Arnoldo J.
dc.contributor.authorSerrano, Carolina A.
dc.contributor.authorHarris, Paul R.
dc.date.accessioned2025-01-20T20:22:51Z
dc.date.available2025-01-20T20:22:51Z
dc.date.issued2022
dc.description.abstractBackground: The urea breath test (UBT-13C) is a non-invasive technique that allows the diagnosis and confirmation of eradication of Helicobacter pylori infection. Aim: To evaluate H. pylori positivity and values of UBT-C-13 among infected Chilean children and adults, and to analyze its variation in relation to sex, nutritional status, and age of the patients. Material and Methods: Retrospective study of 1141 patients aged 6 to 94 years, with an indication for a UBT-C-13 either for diagnosis or for confirmation of eradication of H. pylori infection. C-13 enrichment was measured using an infrared spectrometer calculating the delta C-13 values before and after the ingestion of C-13 marked urea. The clinical data of the patients were obtained at the time of the examination. Results: We included 241 children and 900 adults. Infected children obtained lower UBT-C-13 delta values than infected adults (16.1 +/- 8.7 and 37 +/- 52.9, respectively). The rates of infection were higher in males who were recruited for diagnosis. Significant differences were obtained between positivity for H. pylori in overweight and obese children but not adults. UBT-C-13 titers were significantly associated with the body mass index (BMI) only in adults. Conclusions: H. pylori infection rates are similar between sexes and are higher in children probably because of selection bias. In children, H. pylori positivity is associated with higher BMI and excess malnutrition although with similar UBT-C-13 values. In adults, H. pylori infection is not related with BMI, but a higher BMI impacts UBT-C-13 titers.
dc.fuente.origenWOS
dc.identifier.eissn0717-6163
dc.identifier.issn0034-9887
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/92697
dc.identifier.wosidWOS:001002197900007
dc.issue.numero11
dc.language.isoen
dc.pagina.final1476
dc.pagina.inicio1467
dc.revistaRevista medica de chile
dc.rightsacceso restringido
dc.subjectBody Mass Index
dc.subjectBreath Tests
dc.subjectUrea
dc.subjectHelicobacter pylori
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.title<i>Helicobacter pylori</i> infection and UBT-<SUP>13</SUP>C values are associated with changes in body mass index in children and adults
dc.typeartículo
dc.volumen150
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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