Hemolytic uremic syndrome in a child with leukemia and cytomegalovirus infection

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dc.contributor.authorCavagnaro, F
dc.contributor.authorBarriga, F
dc.date.accessioned2025-01-21T01:31:10Z
dc.date.available2025-01-21T01:31:10Z
dc.date.issued2000
dc.description.abstractA 2-year-old boy had a severe cytomegalovirus (CMV) infection with multi-organ involvement, while on maintenance therapy for acute lymphoblastic leukemia. The patient was treated with intravenous gancyclovir, with a marked improvement in his clinical status, with the exception of a progressive deterioration of the renal function. He also developed hemolytic anemia and thrombocytopenia, suggesting a diagnosis of atypical hemolytic uremic syndrome (HUS). A percutaneous renal biopsy showed lesions consistent with HUS, but no evidence of CMV infection. The patient had a good clinical outcome with no evidence of renal sequelae. We report a rare association of CMV infection and HUS in the pediatric age-group, which suggests a possible cause-effect relationship that deserves further evaluation.
dc.fuente.origenWOS
dc.identifier.issn0931-041X
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/97001
dc.identifier.wosidWOS:000089751400013
dc.issue.numero12
dc.language.isoen
dc.pagina.final1120
dc.pagina.inicio1118
dc.revistaPediatric nephrology
dc.rightsacceso restringido
dc.subjecthemolytic uremic syndrome
dc.subjectcytomegalovirus
dc.subjectacute renal failure
dc.subjectacute lymphoblastic leukemia
dc.subjectperitoneal dialysis
dc.subjectthrombotic microangiopathy
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleHemolytic uremic syndrome in a child with leukemia and cytomegalovirus infection
dc.typeartículo
dc.volumen14
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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