Prevalence of virulence genes in strains of <i>Campylobacter jejuni</i> isolated from human, bovine and broiler

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dc.contributor.authorGonzalez-Hein, Gisela
dc.contributor.authorHuaracan, Bernardo
dc.contributor.authorGarcia, Patricia
dc.contributor.authorFigueroa, Guillermo
dc.date.accessioned2025-01-24T00:07:03Z
dc.date.available2025-01-24T00:07:03Z
dc.date.issued2013
dc.description.abstractCampylobacter jejuni isolates of different origins (bovine, broiler meat, human) were screened by polymerase chain reaction for the presence of 4 genes cdtB, cst-II, ggt, and virB11, previously linked to virulence such as adherence, invasion, colonization, molecular mimicry, and cytotoxin production. In addition, the isolates were screened for the presence of the global gene regulator csrA linked to oxidative stress responses, biofilms formation, and cell adhesion. All the C. jejuni isolates were positive for cdtB gene. The csrA gene was detected in 100% and 92% of C. jejuni isolates from human and animal origin and the virB11 gene was detected in 7.3% and 3.6% isolates from chicken and human respectively. All isolates from bovine were negative for the virB11 gene. The isolates showed a wide variation for the presence of the remaining genes. Of the C. jejuni recovered from human 83.6%, and 32.7% were positive for cst-II, and ggt respectively. Out of the isolates from chicken 40% and 5.5% isolates revealed the presence of cst-II, and ggt, respectively. Finally of the C. jejuni isolates from bovine, 97.7% and 22.7% were positive for cst-II, and ggt respectively. We conclude that the genes of this study circulate among humans and animals. These results led us to hypothesize that the isolates associated with enteritis (cdtB positives) are not selected by environmental or host-specific factors. On the other hand, the high frequencies of csrA gene in C. jejuni show that this gene is important for the survival of C. jejuni in animals and humans.
dc.description.funderNational Commission for Scientific and Technological Research (CONICYT for its acronym in Spanish)
dc.fuente.origenWOS
dc.identifier.eissn1678-4405
dc.identifier.issn1517-8382
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/101891
dc.identifier.wosidWOS:000333959600028
dc.issue.numero4
dc.language.isoen
dc.pagina.final1229
dc.pagina.inicio1223
dc.revistaBrazilian journal of microbiology
dc.rightsacceso restringido
dc.subjectCampylobacter jejuni
dc.subjectvirulence
dc.subjectGuillain Barre syndrome
dc.subjectbroiler
dc.subjectbovine
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titlePrevalence of virulence genes in strains of <i>Campylobacter jejuni</i> isolated from human, bovine and broiler
dc.typeartículo
dc.volumen44
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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