Maternal outcomes and risk factors for COVID-19 severity among pregnant women

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dc.contributor.authorVouga, Manon
dc.contributor.authorFavre, Guillaume
dc.contributor.authorPomar, Leo
dc.contributor.authorForcen Acebal, Laura
dc.contributor.authorAbascal-Saiz, Alejandra
dc.contributor.authorVila Hernandez, Maria Rosa
dc.contributor.authorHcini, Najeh
dc.contributor.authorLambert, Veronique
dc.contributor.authorCarles, Gabriel
dc.contributor.authorSichitiu, Joanna
dc.contributor.authorSalomon, Laurent
dc.contributor.authorStirnemann, Julien
dc.contributor.authorVille, Yves
dc.contributor.authorde Tejada, Begona Martinez
dc.contributor.authorGonce, Anna
dc.contributor.authorCastillo, Karen
dc.contributor.authorGratacos Solsona, Eduard
dc.contributor.authorTrigo, Lucas
dc.contributor.authorCleary, Brian
dc.contributor.authorGeary, Michael
dc.contributor.authorBartels, Helena
dc.contributor.authorMalone, Fergal
dc.contributor.authorHiggins, Mary
dc.contributor.authorKeating, Niamh
dc.contributor.authorKnowles, Susan
dc.contributor.authorPoncelet, Christophe
dc.contributor.authorSurita, Fernanda
dc.contributor.authorBorrelli, Carolina
dc.contributor.authorLuz, Adriana Gomes
dc.contributor.authorFuenzalida, Javiera
dc.contributor.authorCarvajal, Jorge
dc.contributor.authorGuerra Canales, Manuel
dc.contributor.authorHernandez, Olivia
dc.contributor.authorGrechukhina, Olga
dc.contributor.authorKo, Albert, I
dc.contributor.authorReddy, Uma
dc.contributor.authorFigueiredo, Rita
dc.contributor.authorMoucho, Marina
dc.contributor.authorPinto, PedroViana
dc.contributor.authorDe Luca, Carmen
dc.contributor.authorDe Santis, Marco
dc.contributor.authorde Campos, Diogo Ayres
dc.contributor.authorMartins, Ines
dc.contributor.authorGarabedian, Charles
dc.contributor.authorSubtil, Damien
dc.contributor.authorBohrer, Betania
dc.contributor.authorDa Rocha Oppermann, Maria Lucia
dc.contributor.authorOsorioWender, Maria Celeste
dc.contributor.authorVieira Sanseverino, Maria Teresa
dc.contributor.authorGiugliani, Camila
dc.contributor.authorFriedrich, Luciana
dc.contributor.authorScherer, Mariana Horn
dc.contributor.authorMottet, Nicolas
dc.contributor.authorDucarme, Guillaume
dc.contributor.authorPelerin, Helene
dc.contributor.authorMoreau, Chloe
dc.contributor.authorBreton, Benedicte
dc.contributor.authorQuibel, Thibaud
dc.contributor.authorRozenberg, Patrick
dc.contributor.authorGiannoni, Eric
dc.contributor.authorGranado, Cristina
dc.contributor.authorMonod, Cecile
dc.contributor.authorMueller, Doris
dc.contributor.authorHoesli, Irene
dc.contributor.authorBassler, Dirk
dc.contributor.authorHeldstab, Sandra
dc.contributor.authorKolble, Nicole Ochsenbein
dc.contributor.authorSentilhes, Loic
dc.contributor.authorCharvet, Melissa
dc.contributor.authorDeprest, Jan
dc.contributor.authorRichter, Jute
dc.contributor.authorVan der Veeken, Lennart
dc.contributor.authorEggel-Hort, Beatrice
dc.contributor.authorPlantefeve, Gaetan
dc.contributor.authorDerouich, Mohamed
dc.contributor.authorNieto Calvache, Albaro Jose
dc.contributor.authorHecher, Kurt
dc.contributor.authorHadar, Eran
dc.contributor.authorHaratz, Karina Krajden
dc.contributor.authorAmikam, Uri
dc.contributor.authorMalinger, Gustavo
dc.contributor.authorMaymon, Ron
dc.contributor.authorYogev, Yariv
dc.contributor.authorSchafer, Leonhard
dc.contributor.authorToussaint, Arnaud
dc.contributor.authorRossier, Marie-Claude
dc.contributor.authorDe Sa, RenatoAugusto Moreira
dc.contributor.authorGrawe, Claudia
dc.contributor.authorAebi-Popp, Karoline
dc.contributor.authorRaio, Luigi
dc.contributor.authorSurbek, Daniel
dc.contributor.authorBockenhof, Paul
dc.contributor.authorStrizek, Brigitte
dc.contributor.authorKaufmann, Martin
dc.contributor.authorBloch, Andrea
dc.contributor.authorBoulvain, Michel
dc.contributor.authorJohann, Silke
dc.contributor.authorHeldstab, SandraAndrea
dc.contributor.authorBernasconi, MonyaTodesco
dc.contributor.authorGrant, Gaston
dc.contributor.authorFeki, Anis
dc.contributor.authorMuller Brochut, Anne-Claude
dc.contributor.authorGiral, Marylene
dc.contributor.authorSedille, Lucie
dc.contributor.authorPapadia, Andrea
dc.contributor.authorBrugger, Romina Capoccia
dc.contributor.authorWeber, Brigitte
dc.contributor.authorFischer, Tina
dc.contributor.authorKahlert, Christian
dc.contributor.authorSaines, Karin Nielsen
dc.contributor.authorCambou, Mary
dc.contributor.authorKanellos, Panagiotis
dc.contributor.authorChen, Xiang
dc.contributor.authorYin, Mingzhu
dc.contributor.authorHaessig, Annina
dc.contributor.authorAckermann, Sandrine
dc.contributor.authorBaud, David
dc.contributor.authorPanchaud, Alice
dc.date.accessioned2025-01-20T22:11:31Z
dc.date.available2025-01-20T22:11:31Z
dc.date.issued2021
dc.description.abstractPregnant women may be at higher risk of severe complications associated with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which may lead to obstetrical complications. We performed a case control study comparing pregnant women with severe coronavirus disease 19 (cases) to pregnant women with a milder form (controls) enrolled in the COVI-Preg international registry cohort between March 24 and July 26, 2020. Risk factors for severity, obstetrical and immediate neonatal outcomes were assessed. A total of 926 pregnant women with a positive test for SARS-CoV-2 were included, among which 92 (9.9%) presented with severe COVID-19 disease. Risk factors for severe maternal outcomes were pulmonary comorbidities [aOR 4.3, 95% CI 1.9-9.5], hypertensive disorders [aOR 2.7, 95% CI 1.0-7.0] and diabetes [aOR2.2, 95% CI 1.1-4.5]. Pregnant women with severe maternal outcomes were at higher risk of caesarean section [70.7% (n=53/75)], preterm delivery [62.7% (n=32/51)] and newborns requiring admission to the neonatal intensive care unit [41.3% (n=31/75)]. In this study, several risk factors for developing severe complications of SARS-CoV-2 infection among pregnant women were identified including pulmonary comorbidities, hypertensive disorders and diabetes. Obstetrical and neonatal outcomes appear to be influenced by the severity of maternal disease.
dc.fuente.origenWOS
dc.identifier.doi10.1038/s41598-021-92357-y
dc.identifier.issn2045-2322
dc.identifier.urihttps://doi.org/10.1038/s41598-021-92357-y
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/94407
dc.identifier.wosidWOS:000672717300009
dc.issue.numero1
dc.language.isoen
dc.revistaScientific reports
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleMaternal outcomes and risk factors for COVID-19 severity among pregnant women
dc.typeartículo
dc.volumen11
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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