The antifungal effect of six commercial extracts of Chilean propolis on <i>Candida</i> spp.

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dc.contributor.authorHerrera, Christian L.
dc.contributor.authorAlvear, Marysol
dc.contributor.authorBarrientos, Leticia
dc.contributor.authorMontenegro, Gloria
dc.contributor.authorSalazar, Luis A.
dc.date.accessioned2025-01-21T00:07:05Z
dc.date.available2025-01-21T00:07:05Z
dc.date.issued2010
dc.description.abstractC. L. Herrera, M. Alvear, L. Barrientos, C. Montenegro, and L. A. Salazar. 2010. The antifungal effect of six commercial extracts of Chilean propolis on Candida spp. Cien. Inv. Agr. 37(1): 75 - 84. Propolis has been used in traditional medicine for many centuries because of its beneficial health properties, including its antimicrobial capacity. Prosthesis stomatitis affects a significant percentage of users of removable dentures; Candida albicans is the most common fungal species associated with the development of this pathology. Thus, the objectives of this study were: a. To evaluate the antifungal activity of six commercial propolis extracts against Candida spp. that was isolated from the oral cavity of removable dentures users, and b. To determine chemical characteristics of the propolis extracts evaluated. Among the results, we note that these concentrations of polyphenols varied between 9 +/- 0.3 and 85 +/- 2.1 mg mL(-1). Chromatographic analysis was able to detect 35 compounds, among which were caffeic acid, myricetin, quercetin, kaempferol, apigenin. pinocembrin, galangin, and caffeic acid phenyl ester (CAPE). All strains tested were inhibited by the liquid extracts of propolis. The MID ranged between 1:40 and 1:1280, and the MIC for C. albicans ranged from 197 mu g mL(-1) to 441 mu g mL(-1). From the results obtained in this investigation, we can conclude that all propolis extracts evaluated are capable of inhibiting the development of Candida spp. However, they show significant differences in the concentration of polyphenols present and in antifungal activity.
dc.fuente.origenWOS
dc.identifier.issn0718-1620
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/95615
dc.identifier.wosidWOS:000277157200007
dc.issue.numero1
dc.language.isoen
dc.pagina.final84
dc.pagina.inicio75
dc.revistaCiencia e investigacion agraria
dc.rightsacceso restringido
dc.subjectAntifungal activity
dc.subjectCandida albicans
dc.subjectpropolis
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleThe antifungal effect of six commercial extracts of Chilean propolis on <i>Candida</i> spp.
dc.typeartículo
dc.volumen37
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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