Study of degradation of norfloxacin antibiotic and their intermediates by natural solar photolysis

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dc.contributor.authorRivera-Vera, Camilo
dc.contributor.authorMunoz-Lira, Daniela
dc.contributor.authorAranda, Mario
dc.contributor.authorToledo-Neira, Carla
dc.contributor.authorSalazar, Ricardo
dc.date.accessioned2025-01-20T20:19:10Z
dc.date.available2025-01-20T20:19:10Z
dc.date.issued2023
dc.description.abstractIn this work, the photolysis of the antibiotic norfloxacin (NOR) and the formation of its photodegradation products were studied using UV and solar radiation. Their extraction was also assessed in Milli-Q water and secondary effluents from a wastewater treatment plant. The photolysis of NOR was chromatographically monitored. The structure of each degradation product is related to the reaction of NOR with reactive oxygen species (ROS), as confirmed using radical quenchers and mass spectrometry. Additionally, the feasibility of extracting NOR and its degradation products was assessed using a commercial solid phase extraction system. Photolysis results showed the formation of five degradation products, generated under exposure to both types of radiation. The decays in NOR concentrations for the solar and UV treatments were adjusted to pseudo first-order kinetics with apparent constant values of k(solar) = 1.19 x 10(-3) s(-1) and k(UV) = 3.84 x 10(-5) s(-1). Furthermore, the superoxide radical was the main participant species in the formation of the degradation products P3, P4, and P5. Species P1 and P2 do not need this radical for their formation. The presence of NOR in water opens the possibility of its photolysis by solar radiation. This work contributes to the understanding of the mechanisms that mediate its photodegradation, in addition to studying potential options for its determination and its photodegradation products in the sample treatment.
dc.fuente.origenWOS
dc.identifier.doi10.1007/s11356-022-24891-9
dc.identifier.eissn1614-7499
dc.identifier.issn0944-1344
dc.identifier.urihttps://doi.org/10.1007/s11356-022-24891-9
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/92507
dc.identifier.wosidWOS:000911910500012
dc.issue.numero14
dc.language.isoen
dc.pagina.final41027
dc.pagina.inicio41014
dc.revistaEnvironmental science and pollution research
dc.rightsacceso restringido
dc.subjectNorfloxacin antibiotic
dc.subjectSolid-phase extraction
dc.subjectPhotodegradation products
dc.subjectHigh-performance liquid chromatography-mass spectrometry
dc.subjectSolar radiation
dc.subjectUV radiation
dc.subject.ods03 Good Health and Well-being
dc.subject.ods06 Clean Water and Sanitation
dc.subject.odspa03 Salud y bienestar
dc.subject.odspa06 Agua limpia y saneamiento
dc.titleStudy of degradation of norfloxacin antibiotic and their intermediates by natural solar photolysis
dc.typeartículo
dc.volumen30
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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