Vena cava thrombectomy in kidney cancer. Report of 32 nephrectomies

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dc.contributor.authorRojas, Pablo A.
dc.contributor.authorBravo, Juan Cristobal
dc.contributor.authorNavarro, Renato
dc.contributor.authorVillagran, Sofia
dc.contributor.authorZuniga, Alvaro
dc.contributor.authorTroncoso, Pablo
dc.contributor.authorBecker, Pedro
dc.contributor.authorBriceno, Eduardo
dc.contributor.authorFrancisco, Ignacio F. San
dc.date.accessioned2025-01-20T21:00:39Z
dc.date.available2025-01-20T21:00:39Z
dc.date.issued2022
dc.description.abstractBackground: Vena cava (VC) involvement in kidney tumors occurs in 4 to 10% of cases, and is associated with a higher mortality. Nephrectomy with thrombectomy of the VC, performed by a multidisciplinary team, improves survival. Aim: To report a series of consecutive nephrectomies with caval thrombectomy performed in an academic center. Patients and Methods: We report 32 patients with cT3b and 3c renal tumors, who underwent radical nephrectomy with VC thrombectomy between 2001 and 2021. A descriptive analysis of clinical, surgical and pathological variables was performed. Overall survival (OS) and cancer-specific survival (CSS) was calculated using Kaplan-Meier curves. Results: The mean tumor size was 9.7 cm. According to Mayo classification 3/32 (9%) patients had a type I thrombus, 10/32 (31%) had a type II thrombus, 8/32 (25%) had a type III thrombus, and 5/32 (16%) had a type IV thrombus. The mean bleeding was 2000 cc. There was one intraoperative death. Nineteen percent of patients had complications >= 3 according to Clavien-Dindo classification. Reoperations occurred in 9%. Pre and postoperative creatinine levels were 1.17 and 1.91 mg/dl respectively (p < 0.01). Pre and postoperative Hematocrit levels were 47.9 and 31% respectively (p = 0.02). Sixty six percent of tumors were clear cell renal cancer, 9% were papillary and 3% were chromophobic. Mean OS was 10 months. Two-year SCE was 40%. Conclusions: Our results are similar to those reported elsewhere. Despite being an unusual pathology, the surgical technique has been improving, thanks to the multidisciplinary work of urologists and surgeons.
dc.fuente.origenWOS
dc.identifier.eissn0717-6163
dc.identifier.issn0034-9887
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/92722
dc.identifier.wosidWOS:000968680200002
dc.issue.numero8
dc.language.isoen
dc.pagina.final999
dc.pagina.inicio994
dc.revistaRevista medica de chile
dc.rightsacceso restringido
dc.subjectKidney Neoplasms
dc.subjectNephrectomy
dc.subjectVenae Cavae
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleVena cava thrombectomy in kidney cancer. Report of 32 nephrectomies
dc.typeartículo
dc.volumen150
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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