Diagnóstico de la infección por Helicobacter pylori en niños mediante la detección de antígenos en deposiciones

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dc.catalogadorpau
dc.contributor.authorGonzález, Carmen Gloria
dc.contributor.authorSerrano, Carolina
dc.contributor.authorHarris, Paul R.
dc.date.accessioned2024-01-19T19:22:44Z
dc.date.available2024-01-19T19:22:44Z
dc.date.issued2007
dc.description.abstractBackground: During infancy, preventive, diagnostic and therapeutic efforts for Helicobacter pylori infection should be made. Aim: To evaluate non-invasive diagnostic methods such as stool antigen test (HpSA) and serum anti-H pylori antibody detection (IgG e IgA), compared to endoscopy-based invasive methods (histology and urease test) for the diagnosis of Helicobacter pylori infection. Patients and Methods: Thirty nine children (aged 3 to 14 years, 20 males) referred for upper gastrointestinal endoscopy, were studied. The gold standard to diagnose Helicobacter pylori infection was defined as a positive invasive diagnostic test (histology and/or urease test). Sensitivity (S), specificity (E) and positive (PPV) and negative (NPV) predictive values were obtained for HpSA and serum antibodies. Results: Ten children (26%) were infected with H pylori. S, E, PPV and NPV for HpSA were 90, 100, 100 and 97%, respectively. The figures for serum IgG were 81, 97, 89 and 93%, respectively and for IgA, 90, 76, 36 and 96%, respectively. Conclusions: HpSA was sensitive and specific as a clinical and epidemiological tool to evaluate H pylori infection in children. Serology was not as accurate, but IgG had a better performance than IgA. © 2007 Sociedad Médica de Santiago.
dc.fuente.origenORCID-ene24
dc.identifier.issn0717-9367
dc.identifier.urihttp://www.scopus.com/inward/record.url?eid=2-s2.0-33947603884&partnerID=MN8TOARS
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/80837
dc.information.autorucEscuela de Medicina; Harris Diez, Paul Richard; 0000-0001-6226-0957; 80706
dc.issue.numero2
dc.language.isoes
dc.nota.accesoContenido completo
dc.revistaRevista Médica de Chile
dc.rightsacceso abierto
dc.subjectAntibodieses_ES
dc.subjectBacteriales_ES
dc.subjectHelicobacter pylories_ES
dc.subjectImmunoglobulinses_ES
dc.titleDiagnóstico de la infección por Helicobacter pylori en niños mediante la detección de antígenos en deposicioneses_ES
dc.title.alternativeDiagnosis of Helicobacter pylori infection in children based on stool antigen test
dc.typeartículo
dc.volumen135
sipa.codpersvinculados80706
sipa.trazabilidadORCID;2024-01-08
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