Insulin settings and their association with time in range in patients with type 1 diabetes users of predictive low glucose suspend (PLGS) augmented insulin pumps in Santiago, Chile

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dc.contributor.authorGrassi, Bruno A.
dc.contributor.authorCarames, Belen
dc.contributor.authorCristian Plaza-Plaza, Jose
dc.contributor.authorTeresa Onetto, Maria
dc.contributor.authorMoreno, Sebastian
dc.contributor.authorSandoval, Trinidad
dc.contributor.authorTapia, Nicole
dc.contributor.authorMena, Francisca
dc.contributor.authorRevello, Alejandro
dc.date.accessioned2025-01-20T21:02:45Z
dc.date.available2025-01-20T21:02:45Z
dc.date.issued2022
dc.description.abstractAims: Sensor augmented insulin pumps have become a powerful tool for managing type 1 diabetes (T1D). This study aimed to analyze the insulin pump configuration in users of predictive insulin suspension technology (PLGS).Methods: T1D patients on insulin pumps with PLGS (Medtronic 640G (R)) were enrolled. Data was obtained from medical records and pump data was downloaded for 30 days. Basal insulin, bolus calculator parameters, and PLGS operation parameters were analyzed and compared with Time in Range, Time Below Range, and Time Above Range.Results: 112 patients were included, with average TIR of 73,96 % and HbA1c 7,0 % and 25 months of follow-up. Basal insulin remained similar to initial doses, with an increase of 27 % for the Dawn phenomenon. The Car-bohydrate ratio was slightly more aggressive. Insulin sensitivity was 17 % less stringent than initially pro-grammed. No differences were observed in Time in Rage according to the number of basal, ratio, and sensitivity segments. Time of insulin suspension correlated directly with Time Bellow Range. Conclusions: Patients with good metabolic control have basal insulin programming similar to their initiation doses with less aggressive sensitivity factors. Excessive suspension time determined by PLGS could be an expression of excess insulin and increased hypoglycemia risk.
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.jdiacomp.2022.108262
dc.identifier.eissn1873-460X
dc.identifier.issn1056-8727
dc.identifier.urihttps://doi.org/10.1016/j.jdiacomp.2022.108262
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/93080
dc.identifier.wosidWOS:000848035100014
dc.issue.numero8
dc.language.isoen
dc.revistaJournal of diabetes and its complications
dc.rightsacceso restringido
dc.subjectType 1 diabetes
dc.subjectInsulin pumps
dc.subjectPredictive low glucose suspend
dc.subjectContinuous glucose monitoring
dc.subjectDiabetes education
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleInsulin settings and their association with time in range in patients with type 1 diabetes users of predictive low glucose suspend (PLGS) augmented insulin pumps in Santiago, Chile
dc.typeartículo
dc.volumen36
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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