ACTIN-LIKE FILAMENTS AND MEMBRANE REARRANGEMENT IN OXYNTIC CELLS

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dc.contributor.authorVIAL, JD
dc.contributor.authorGARRIDO, J
dc.date.accessioned2025-01-23T19:44:59Z
dc.date.available2025-01-23T19:44:59Z
dc.date.issued1976
dc.description.abstractThe secretory pole of vertebrate oxyntic cells possesses 2 distinct membrane systems: the apical plasma membrane which presents numerous infoldings, microvilli and processes and a complex tubulovesicular system located in close proximity to the plasma membrane. These 2 membrane systems are generally believed to be interconvertible in relation to the functional state of the cell. To determine the role that filaments may play in the interconversion process, the secretory pole of rat and toad [Bufo spinulosus] oxyntic cells was examined by EM under conditions designed to demonstrate filamentous structures, i.e., slight cellular swelling and incubation with heavy meromyosin. Filaments 50-80 .ANG. in diameter are present in close association with the plasma membrane to which they are connected by regularly spaced bridges. Heavy meromyosin-treated material reveals decorated filaments in topographically corresponding locations. No filaments are seen in association with membranes of the tubulovesicular system. Association with actin-like filaments may be a step in the translocation of membranes from the tubulovesicular system to the plasma membrane.
dc.fuente.origenWOS
dc.identifier.eissn1091-6490
dc.identifier.issn0027-8424
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/100177
dc.identifier.wosidWOS:A1976CN11500053
dc.issue.numero11
dc.language.isoen
dc.pagina.final4036
dc.pagina.inicio4032
dc.revistaProceedings of the national academy of sciences of the united states of america
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleACTIN-LIKE FILAMENTS AND MEMBRANE REARRANGEMENT IN OXYNTIC CELLS
dc.typeartículo
dc.volumen73
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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