ISOLATION OF PROTEOGLYCANS SYNTHESIZED BY RAT-HEART - EVIDENCE FOR THE PRESENCE OF SEVERAL DISTINCT FORMS

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dc.contributor.authorGONZALEZ, R
dc.contributor.authorURREA, R
dc.contributor.authorGONZALEZ, M
dc.contributor.authorINESTROSA, NC
dc.contributor.authorBRANDAN, E
dc.date.accessioned2025-01-23T19:22:17Z
dc.date.available2025-01-23T19:22:17Z
dc.date.issued1992
dc.description.abstract1. The proteoglycans (Ps) synthesized by auricle and ventricle from adult rat
dc.description.abstract2. Auricle tissue incorporated over two times radioactive sulfate compared to ventricle tissue and the Ps were mainly found in the detergent insoluble fraction. 3. The Ps from both tissues were isolated by ion-exchange chromatography on DEAE-Sephacel, followed by gel filtration on Sepharose CL-6B and SDS-PAGE electrophoresis.
dc.description.abstract4. Enzymatic and chemical degradation of these Ps suggest that at least three and probably four different species of Ps can be observed in heart tissue.
dc.description.abstract4. A high molecular weight chondroitin sulfate-P, a high molecular weight heparan sulfate-P, a chondroitin/dermatan sulfate-P of 240-200 kDa and a dermatan sulfate of 115 kDa.
dc.description.abstract5. This latter P was specifically immunoprecipitated using rat decorin antiserum.
dc.fuente.origenWOS
dc.identifier.issn0306-3623
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/99008
dc.identifier.wosidWOS:A1992HF71500020
dc.issue.numero2
dc.language.isoen
dc.pagina.final255
dc.pagina.inicio249
dc.revistaGeneral pharmacology
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleISOLATION OF PROTEOGLYCANS SYNTHESIZED BY RAT-HEART - EVIDENCE FOR THE PRESENCE OF SEVERAL DISTINCT FORMS
dc.typeartículo
dc.volumen23
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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