Incidence of liver cancer in young adults according to the Global Burden of Disease database 2019

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dc.catalogadorvdr
dc.contributor.authorDanpanichkul, Pojsakorn
dc.contributor.authorAboona, Majd B.
dc.contributor.authorSukphutanan, Banthoon
dc.contributor.authorKongarin, Siwanart
dc.contributor.authorDuangsonk, Kwanjit
dc.contributor.authorNg, Cheng Han
dc.contributor.authorMuthiah, Mark D.
dc.contributor.authorHuang, Daniel Q.
dc.contributor.authorSeko, Yuya
dc.contributor.authorDiaz Piga, Luis Antonio
dc.contributor.authorArab Verdugo, Juan Pablo
dc.contributor.authorYang, Ju Dong
dc.contributor.authorChen, Vincent L.
dc.contributor.authorKim, Donghee
dc.contributor.authorNoureddin, Mazen
dc.contributor.authorLiangpunsakul, Suthat
dc.contributor.authorWijarnpreecha, Karn
dc.date.accessioned2024-11-22T17:41:55Z
dc.date.available2024-11-22T17:41:55Z
dc.date.issued2024
dc.description.abstractBackground and Aims: The worldwide burden of cancer is increasing in younger populations. However, the epidemiology of primary liver cancer remains understudied in young adults compared to other cancer forms., Approach and Results: This study analyzed data from the Global Burden of Disease study between 2010 and 2019 to assess the age-standardized incidence, mortality, and disability-adjusted life years associated with primary liver cancer in the young (15-49 y), stratified by region, nation, sociodemographic index, and sex. The study found a global estimate of 78,299 primary liver cancer cases, 60,602 deaths, and 2.90 million disability-adjusted life years in the young population. The Western Pacific region exhibited the highest burden in 2019, showing the most significant increase compared to other regions between 2010 and 2019. More than half of the countries worldwide have undergone an increase in primary liver cancer incidence rates in young adults. Around 12.51% of deaths due to primary liver cancer occur in young individuals. Throughout the study period, there was a significant decline in primary liver cancer mortality due to most etiologies, except for metabolic dysfunction-associated steatotic liver disease-attributable primary liver cancer (annual percentage change + 0.87%, 95% CI: 0.70%-1.05%) and alcohol-attributable primary liver cancer (annual percentage change + 0.21%, 95% CI: 0.01%-0.42%). The limitations of the Global Burden of Disease database include reliance on the quality of primary data and possible underestimation of alcohol consumption., Conclusions: Over the past decade, there has been a marked increase in the burden of primary liver cancer, especially that originating from steatotic liver disease. This trend calls for the development of urgent and comprehensive strategies to mitigate this rising burden globally.
dc.fuente.origenWOS
dc.fuente.origenORCID
dc.identifier.doi10.1097/HEP.0000000000000872
dc.identifier.eissn1527-3350
dc.identifier.urihttps://doi.org/10.1097/HEP.0000000000000872
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/88650
dc.identifier.wosidWOS:001241301700001
dc.information.autorucEscuela de Medicina; Diaz Piga, Luis Antonio; 0000-0002-8540-4930; 179253
dc.information.autorucEscuela de Medicina; Arab Verdugo, Juan Pablo; 0000-0002-8561-396X; 132745
dc.issue.numero4
dc.language.isoen
dc.nota.accesosin adjunto
dc.revistaHepatology
dc.rightsregistro bibliográfico
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titleIncidence of liver cancer in young adults according to the Global Burden of Disease database 2019
dc.typeartículo
dc.volumen80
sipa.codpersvinculados179253
sipa.codpersvinculados132745
sipa.trazabilidadWOS;2024-06-15
sipa.trazabilidadORCID;2024-11-18
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