Psychological treatment of perinatal depression: a meta-analysis

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dc.contributor.authorCuijpers, Pim
dc.contributor.authorFranco, Pamela
dc.contributor.authorCiharova, Marketa
dc.contributor.authorMiguel, Clara
dc.contributor.authorSegre, Lisa
dc.contributor.authorQuero, Soledad
dc.contributor.authorKaryotaki, Eirini
dc.date.accessioned2025-01-20T20:21:43Z
dc.date.available2025-01-20T20:21:43Z
dc.date.issued2023
dc.description.abstractBackground. Depression during pregnancy and after the birth of a child is highly prevalent and an important public health problem. Psychological interventions are the first-line treatment and, although a considerable number of randomized trials have been conducted, no recent comprehensive meta-analysis has evaluated treatment effects.
dc.description.abstractMethods. We used an existing database of randomized controlled trials of psychotherapies for adult depression and included studies aimed at perinatal depression. Random effects models were used in all analyses. We examined the effects of the interventions in the short and long term, and also examined secondary outcomes.
dc.description.abstractResults. Forty-three studies with 49 comparisons and 6270 participants between an intervention and control group were included. The overall effect size was g= 0.67 [95% confidence interval (CI) 0.45 similar to 0.89; numbers needed-to-be-treated = 4.39] with high heterogeneity (I-2 = 80%; 95% CI 75 similar to 85). This effect size remained largely unchanged and significant in a series of sensitivity analyses, although some publication bias was found. The effects remained significant at 6-12 months follow-up. Significant effects were also found for social support, anxiety, functional limitations, parental stress and marital stress, although the number of studies for each outcome was low. All results should be considered with caution because of the high levels of heterogeneity in most analyses.
dc.description.abstractConclusions. Psychological interventions are probably effective in the treatment of perinatal depression, with effects that last at least up to 6-12 months and probably also have effects on social support, anxiety, functional impairment, parental stress, and marital stress.
dc.fuente.origenWOS
dc.identifier.doi10.1017/S0033291721004529
dc.identifier.eissn1469-8978
dc.identifier.issn0033-2917
dc.identifier.urihttps://doi.org/10.1017/S0033291721004529
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/92641
dc.identifier.wosidWOS:000786822000001
dc.issue.numero6
dc.language.isoen
dc.pagina.final2608
dc.pagina.inicio2596
dc.revistaPsychological medicine
dc.rightsacceso restringido
dc.subjectAntenatal depression
dc.subjectcognitive behavior therapy
dc.subjectinterpersonal psychotherapy
dc.subjectmeta-analysis
dc.subjectperinatal depression
dc.subjectpostpartum depression
dc.subjectrandomized controlled trials
dc.subject.ods03 Good Health and Well-being
dc.subject.ods05 Gender Equality
dc.subject.odspa03 Salud y bienestar
dc.subject.odspa05 Igualdad de género
dc.titlePsychological treatment of perinatal depression: a meta-analysis
dc.typeartículo
dc.volumen53
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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