Surgical results of video-assisted thoracoscopic thymectomy for treatment of Juvenile Myasthenia Gravis

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dc.contributor.authorSaez, Josefina
dc.contributor.authorJesus Irarrazaval, Maria
dc.contributor.authorVidal, Cristina
dc.contributor.authorPeralta, Felipe
dc.contributor.authorEscobar, Raul G.
dc.contributor.authorAvila, Daniela
dc.contributor.authorConcha, Mario
dc.contributor.authorVuletin, Fernando
dc.contributor.authorCarlos Pattillo, Juan
dc.date.accessioned2025-01-20T23:53:45Z
dc.date.available2025-01-20T23:53:45Z
dc.date.issued2021
dc.description.abstractJuvenile myasthenia gravis (JMG) is an autoimmune disease affecting the neuromuscular junction that appears before 19 years of age with varying degrees of weakness of different muscle groups. The main treatment is pharmacological, but thymectomy has also demonstrated to improve remission rates. Objective: To describe the clinical characteristics and postoperative course of pediatric patients with JMG who underwent video-assisted thoracoscopic (VATS) thymectomy. Clinical Serie: Six patients who underwent VATS thymectomy between March 2011 and June 2019. The age range at diagnosis was between 2 and 14 years and the average age at surgery was 7 years. All patients were under treatment with pyridostigmine bromide associated with immunosuppression with corticosteroids before surgery. The interval between diagnosis and thymectomy was 21.5 months on average. VATS was performed by left approach, and there was no perioperative morbidity or mortality. The average hospital stay was 2 days. Three patients remain with no symptoms and without corticotherapy. Two patients were on corticosteroids, but in smaller doses than previous to surgery. One patient presented a crisis requiring hospitalization and ventilatory support during follow-up. Conclusion: VATS thymectomy is part of the treatment for JMG. In this series, it appears as a safe approach and its results were favorable.
dc.fuente.origenWOS
dc.identifier.doi10.32641/andespediatr.v92i2.2955
dc.identifier.eissn2452-6053
dc.identifier.urihttps://doi.org/10.32641/andespediatr.v92i2.2955
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/94992
dc.identifier.wosidWOS:000808817300012
dc.issue.numero2
dc.language.isoen
dc.pagina.final255
dc.pagina.inicio250
dc.revistaAndes pediatrica
dc.rightsacceso restringido
dc.subjectMyasthenia Gravis
dc.subjectThymus
dc.subjectThymectomy
dc.subjectVATS
dc.subjectVideo-assisted thoracoscopy
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleSurgical results of video-assisted thoracoscopic thymectomy for treatment of Juvenile Myasthenia Gravis
dc.typeartículo
dc.volumen92
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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