ANTIGENIC SPECIFICITY OF LYMPHOCYTES ISOLATED FROM VALVULAR SPECIMENS OF RHEUMATIC-FEVER PATIENTS

Simple item page
dc.contributor.authorYOSHINAGA, M
dc.contributor.authorFIGUEROA, F
dc.contributor.authorWAHID, MR
dc.contributor.authorMARCUS, RH
dc.contributor.authorSUH, E
dc.contributor.authorZABRISKIE, JB
dc.date.accessioned2025-01-21T01:34:38Z
dc.date.available2025-01-21T01:34:38Z
dc.date.issued1995
dc.description.abstractT cell lines were established from both valvular specimens and peripheral blood lymphocytes from seven patients with well documented rheumatic heart disease. These cell lines were stimulated with either PHA or streptococcal antigens. Proliferation assays revealed that both valvular and peripheral blood T cell lines reacted to cell wall (CW) and cell membrane (CM) antigens obtained from rheumatic fever associated group A streptococci and not to nephritogenic strains. None of the cell lines reacted to M protein, myosin or other mammalian cytoskeletal proteins. The unique reactivity of rheumatic fever T cell lines only to cellular structures obtained from rheumatogenic strains suggests that these lines react to epitopes specific for antigens obtained from these strains. (C) 1995 Academic Press Limited
dc.fuente.origenWOS
dc.identifier.issn0896-8411
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/97583
dc.identifier.wosidWOS:A1995RR95700011
dc.issue.numero4
dc.language.isoen
dc.pagina.final613
dc.pagina.inicio601
dc.revistaJournal of autoimmunity
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleANTIGENIC SPECIFICITY OF LYMPHOCYTES ISOLATED FROM VALVULAR SPECIMENS OF RHEUMATIC-FEVER PATIENTS
dc.typeartículo
dc.volumen8
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
Files
Collections
Artículos de revistas