COMPARISON OF THE SUBCELLULAR-DISTRIBUTION OF ALVEOLAR SURFACTANT IN 2 MAMMALIAN-SPECIES OF SIMILAR BODY-WEIGHT - CAT AND RABBIT

Simple item page
dc.contributor.authorOYARZUN, MJ
dc.contributor.authorMORGADO, E
dc.contributor.authorDUSSAUBAT, N
dc.contributor.authorLATHROP, ME
dc.contributor.authorITURRIAGA, R
dc.contributor.authorLARRAIN, C
dc.contributor.authorZAPATA, P
dc.date.accessioned2025-01-23T19:22:04Z
dc.date.available2025-01-23T19:22:04Z
dc.date.issued1992
dc.description.abstract1. We studied the total amount and subcellular distribution of alveolar surfactant, extracted through bronchoalveolar lavage of anesthetized cats and rabbits. This was correlated to several morphometric and ventilatory variables of these animals.
dc.description.abstract2. Lung weight was significantly larger in the cat while respiratory frequency and minute ventilation were significantly larger in the rabbit. No significant differences were observed in tidal volume, total lung capacity, PaO2, PaCO2 and pH(a).
dc.description.abstract3. While both species had similar protein contents in the bronchoalveolar lavage, rabbits had larger phospholipid contents, mostly distributed in the lighter, more active subfractions.
dc.description.abstract4. With regard to the estimated values obtained from allometric equations derived for mammals, the rabbit presented a lung weight of nearly one-third of the estimated one, an exceedingly larger minute ventilation (by nearly 60%) and a respiratory frequency twice the calculated one.
dc.description.abstract5. We suggest that the different distribution of alveolar surfactant in these species may be explained by disparities in their ventilatory demands, the rabbit having a higher respiratory frequency and a larger minute ventilation, performed by a mass of lung tissue lower than that corresponding to its body mass.
dc.fuente.origenWOS
dc.identifier.eissn1531-4332
dc.identifier.issn1095-6433
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/98952
dc.identifier.wosidWOS:A1992JG69100012
dc.issue.numero4
dc.language.isoen
dc.pagina.final674
dc.pagina.inicio669
dc.revistaComparative biochemistry and physiology a-molecular & integrative physiology
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleCOMPARISON OF THE SUBCELLULAR-DISTRIBUTION OF ALVEOLAR SURFACTANT IN 2 MAMMALIAN-SPECIES OF SIMILAR BODY-WEIGHT - CAT AND RABBIT
dc.typeartículo
dc.volumen102
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
Files
Collections
Artículos de revistas