SAGExplore: a web server for unambiguous tag mapping in serial analysis of gene expression oriented to gene discovery and annotation

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dc.catalogadoraba
dc.contributor.authorNorambuena, T.
dc.contributor.authorMalig, R.
dc.contributor.authorMelo Ledermann, Francisco Javier
dc.date.accessioned2025-02-06T19:41:06Z
dc.date.available2025-02-06T19:41:06Z
dc.date.issued2007
dc.description.abstractWe describe a web server for the accurate mapping of experimental tags in serial analysis of gene expression (SAGE). The core of the server relies on a database of genomic virtual tags built by a recently described method that attempts to reduce the amount of ambiguous assignments for those tags that are not unique in the genome. The method provides a complete annotation of potential virtual SAGE tags within a genome, along with an estimation of their confidence for experimental observation that ranks tags that present multiple matches in the genome. The output of the server consists of a table in HTML format that contains links to a graphic representation of the results and to some external servers and databases, facilitating the tasks of analysis of gene expression and gene discovery. Also, a table in tab delimited text format is produced, allowing the user to export the results into custom databases and software for further analysis. The current server version provides the most accurate and complete SAGE tag mapping source that is available for the yeast organism. In the near future, this server will also allow the accurate mapping of experimental SAGE-tags from other model organisms such as human, mouse, frog and fly. The server is freely available on the web at: http://dna.bio.puc.cl/SAGExplore.html.
dc.format.extent6 páginas
dc.fuente.origenSIPA
dc.identifier.doi10.1093/nar/gkm429
dc.identifier.eissn1362-4962
dc.identifier.issn0305-1048
dc.identifier.pubmedid17626053
dc.identifier.pubmedidPMC1933165
dc.identifier.scopusid2-s2.0-34547601867
dc.identifier.urihttps://doi.org/10.1093/nar/gkm429
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/102189
dc.identifier.wosidWOS:000255311500032
dc.information.autorucFacultad de Ciencias Biológicas; Melo Ledermann, Francisco Javier; 0000-0002-0424-5991; 82342
dc.issue.numeroSuppl. 2
dc.language.isoen
dc.nota.accesocontenido completo
dc.pagina.finalW168
dc.pagina.inicioW163
dc.revistaNucleic acids research
dc.rightsacceso abierto
dc.rights.licenseAttribution-NonCommercial 2.0 UK: England & Wales
dc.rights.urihttps://creativecommons.org/licenses/by-nc/2.0/uk/
dc.subject.ddc570
dc.subject.deweyBiología
dc.titleSAGExplore: a web server for unambiguous tag mapping in serial analysis of gene expression oriented to gene discovery and annotation
dc.typeartículo
dc.volumen35
sipa.codpersvinculados82342
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