Coagulase-negative staphylococcal prosthetic valve endocarditis-a contemporary update based on the International Collaboration on Endocarditis: prospective cohort study

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dc.contributor.authorChu, V. H.
dc.contributor.authorMiro, J. M.
dc.contributor.authorHoen, B.
dc.contributor.authorCabell, C. H.
dc.contributor.authorPappas, P. A.
dc.contributor.authorJones, P.
dc.contributor.authorStryjewski, M. E.
dc.contributor.authorAnguera, I.
dc.contributor.authorBraun, S.
dc.contributor.authorMunoz, P.
dc.contributor.authorCommerford, P.
dc.contributor.authorTornos, P.
dc.contributor.authorFrancis, J.
dc.contributor.authorOyonarte, M.
dc.contributor.authorSelton-Suty, C.
dc.contributor.authorMorris, A. J.
dc.contributor.authorHabib, G.
dc.contributor.authorAlmirante, B.
dc.contributor.authorSexton, D. J.
dc.contributor.authorCorey, G. R.
dc.contributor.authorFowler, V. G., Jr.
dc.date.accessioned2025-01-21T00:09:26Z
dc.date.available2025-01-21T00:09:26Z
dc.date.issued2009
dc.description.abstractObjective: To describe the contemporary features of coagulase-negative staphylococcal (CoNS) prosthetic valve endocarditis (PVE).
dc.description.abstractDesign: Observational study of prospectively collected data from a multinational cohort of patients with infective endocarditis. Patients with CoNS PVE were compared to patients with Staphylococcus aureus and viridans streptococcal (VGS) PVE.
dc.description.abstractSetting: The International Collaboration on Endocarditis-Prospective Cohort Study (ICE-PCS) is a contemporary cohort of patients with infective endocarditis from 61 centres in 28 countries.
dc.description.abstractPatients: Adult patients in the ICE-PCS with definite PVE and no history of injecting drug use from June 2000 to August 2005 were included.
dc.description.abstractInterventions: None.
dc.description.abstractMain outcome measures: Heart failure, intracardiac abscess, death.
dc.description.abstractResults: CoNS caused 16% (n = 86) of 537 cases of definite non-injecting drug use-associated PVE. Nearly one-half (n = 33/69, 48%) of patients with CoNS PVE presented between 60 days and 365 days of valve implantation. The rate of intracardiac abscess was significantly higher in patients with CoNS PVE (38%) than in patients with either S aureus (23%, p = 0.03) or VGS (20%, p = 0.05) PVE. The rate of abscess was particularly high in early (50%) and intermediate (52%) CoNS PVE. Inhospital mortality was 24% for CoNS PVE, 36% for S aureus PVE (p = 0.09) and 9.1% for VGS PVE (p = 0.08). Meticillin resistance was present in 68% of CoNS strains.
dc.description.abstractConclusions: Nearly one-half of CoNS PVE cases occur between 60 days and 365 days of prosthetic valve implantation. CoNS PVE is associated with a high rate of meticillin resistance and significant valvular complications.
dc.fuente.origenWOS
dc.identifier.doi10.1136/hrt.2008.152975
dc.identifier.issn1355-6037
dc.identifier.urihttps://doi.org/10.1136/hrt.2008.152975
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/95708
dc.identifier.wosidWOS:000264195900012
dc.issue.numero7
dc.language.isoen
dc.pagina.final576
dc.pagina.inicio570
dc.revistaHeart
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleCoagulase-negative staphylococcal prosthetic valve endocarditis-a contemporary update based on the International Collaboration on Endocarditis: prospective cohort study
dc.typeartículo
dc.volumen95
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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