Selective electrochemical determination of dopamine, using a poly(3,4-ethylenedioxythiophene)/polydopamine hybrid film modified electrode

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dc.contributor.authorSalgado, R.
dc.contributor.authordel Rio, R.
dc.contributor.authordel Valle, M. A.
dc.contributor.authorArmijo, F.
dc.date.accessioned2025-01-24T00:08:54Z
dc.date.available2025-01-24T00:08:54Z
dc.date.issued2013
dc.description.abstractThe selective determination of dopamine (DA) was performed in the presence of ascorbic (AA) and uric acid (UA), using a platinum electrode (Pt) modified with a hybrid film of poly(3,4-ethylenedioxythiophene)/polydopamine (PEDOT/PDA). PEDOT was obtained using a potential step technique on a bare Pt electrode. PDA was subsequently obtained on the PEDOT coated electrode by cyclic voltammetry. The PDA thickness effect allows observing just the DA oxidation signal in the presence of some interferents, e.g. uric acid (UA) and ascorbic acid (AA). The formed PEDOT/PDA hybrid film was compared with PEDOT in a K-4[Fe(CN)(6)] solution in PBS of pH 7.4. Inhibition of the [Fe (CN)(6)](4-)/[Fe(CN)(6])(3-) redox couple on the PEDOT/PDA surface was observed, indicating the film bears a negative surface charge. The different electrodes were characterized by SEM and FTIR. DA amperometric determination was performed in the presence of AA and UA. The sensor proved to be selective toward DA. Calibration curves, with a linear range 1.5 x 10(-6) to 50 x 10(-6) mol L-1, enabled the limit of detection and quantification to be determined, namely 0.65 x 10(-6) mol L-1 and 1.77 x 10(-6) mol L-1, respectively. The described methodology permits, therefore, to propose this modified electrode as a new electrode for DA determination in the presence of interferents. (C) 2013 Elsevier B.V. All rights reserved.
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.jelechem.2013.07.005
dc.identifier.eissn1873-2569
dc.identifier.issn1572-6657
dc.identifier.urihttps://doi.org/10.1016/j.jelechem.2013.07.005
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/101972
dc.identifier.wosidWOS:000324658700019
dc.language.isoen
dc.pagina.final136
dc.pagina.inicio130
dc.revistaJournal of electroanalytical chemistry
dc.rightsacceso restringido
dc.subjectDopamine
dc.subjectPoly(3,4-ethylenedioxythiophene)
dc.subjectPolydopamine
dc.subjectModified electrode
dc.subjectAscorbic acid
dc.subjectUric acid
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleSelective electrochemical determination of dopamine, using a poly(3,4-ethylenedioxythiophene)/polydopamine hybrid film modified electrode
dc.typeartículo
dc.volumen704
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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