Diabetic Ketoacidosis in Type 1 Diabetes Onset in Latin American Children

Simple item page
dc.contributor.authorHirschler, Valeria
dc.contributor.authorGonzalez, Claudio D.
dc.contributor.authorKrochik, Gabriela
dc.contributor.authorRousos, Adriana M.
dc.contributor.authorAndres, Maria E.
dc.contributor.authorRiera, Francisca
dc.contributor.authorIbarcena, Paola Pinto
dc.contributor.authorMolinari, Claudia
dc.contributor.authorPorta, Luis F. Palacios
dc.contributor.authorPrieto, Mariana
dc.contributor.authorMateu, Carolina Martinez
dc.contributor.authorBarcala, Consuelo
dc.contributor.authorArrigo, Maria A.
dc.contributor.authorTachetti, Jacqueline.
dc.contributor.authorRaggio, Marcela
dc.contributor.authorVacarezza, Veronica
dc.contributor.authorMajor, Maria L.
dc.contributor.authorSobrero, Angela Figueroa
dc.contributor.authorBogado, Ernesto
dc.contributor.authorLopez, Stella
dc.contributor.authorPovedano, Paula Paz
dc.contributor.authorScaiola, Edit
dc.contributor.authorLeiva, Fabiana
dc.contributor.authorPacheco, Gabriela
dc.contributor.authorPasayo, Patricia
dc.contributor.authorDupuy, Mariana
dc.contributor.authorTorossi, Maria B.
dc.contributor.authorBenitez, Amanda J.
dc.contributor.authorMarassi, Andrea Escalante
dc.contributor.authorCaballero, Zulema
dc.contributor.authorGarcia, Ana L.
dc.contributor.authorMazzetti, Sandra
dc.contributor.authorPugliese, Maria I. Ruiz
dc.contributor.authorGonzalez, Diana S.
dc.contributor.authorGrabois, Florencia
dc.contributor.authorVillar, Carlos M. Del Aguila
dc.contributor.authorFlores, Adriana B.
dc.date.accessioned2025-01-20T16:13:33Z
dc.date.available2025-01-20T16:13:33Z
dc.date.issued2024
dc.description.abstractObjective: To describe the patterns of diabetic ketoacidosis (DKA) occurrence in children newly diagnosed with type 1 diabetes (T1DM) across several Latin American pediatric diabetes centers from 2018 to 2022. Methods: A retrospective chart review included children under 18 with new -onset T1DM from 30 Latin American pediatric diabetes centers (Argentina, Chile, and Peru) between 30 December 2018 and 30 December 2022. Multiple logistic regression models examined the relationships between age, gender, medical insurance, BMI, and DKA at new -onset T1DM. As far as we know, there are no large studies in Latin American countries exploring the patterns of DKA in new -onset T1DM. Results: A total of 2,026 (983 females) children, median age 9.12 (5.8 -11.7) years with new-onset-T1DM were included. Approximately 50% had no medical insurance . Mean glucose values were 467 mg/dL, pH 7.21, bicarbonate 13 mEq/L, HbA1c 11.3%, and BMI 18. The frequency of DKA was 1,229 (60.7%), out of which only 447 (36%) were severe. There was a signi fi cant decrease in the frequency of DKA as age increased : 373 (70.2%) in children under 6, 639 (61.6%) in those between 6 and 12, 217 and (47.5%) in those over 12. Children with medical insurance (58.8%) had a signi fi - cantly lower frequency of DKA than those without (62.7%). The multiple logistic regression models showed that DKA was signi fi - cantly and inversely associated with age [OR, 0.72 (95% CI 0.60 - 0.86)], BMI [OR, 0.95 (95% CI 0.92 - 0.99)], and medical insurance [OR, 0.75 (95% CI 0.60 - 0.94)] adjusted for sex. Conclusion: Latin American children with new -onset T1DM exhibited a substantial occurrence of DKA. Younger ages and the lack of medical insurance were signi fi cantly associated with DKA in new -onset T1DM. J Pediatr Health Care. (2024) 38 , 544 - 551
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.pedhc.2024.01.006
dc.identifier.eissn1532-656X
dc.identifier.issn0891-5245
dc.identifier.urihttps://doi.org/10.1016/j.pedhc.2024.01.006
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/90393
dc.identifier.wosidWOS:001263625400001
dc.issue.numero4
dc.language.isoen
dc.pagina.final551
dc.pagina.inicio544
dc.revistaJournal of pediatric health care
dc.rightsacceso restringido
dc.subjectDiabetic ketoacidosis
dc.subjectonset type 1 diabetes
dc.subjectLatin American children
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleDiabetic Ketoacidosis in Type 1 Diabetes Onset in Latin American Children
dc.typeartículo
dc.volumen38
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
Files
Collections
Artículos de revistas